Preferred Label : Substrate Interaction Domain;
NCIt synonyms : Substrate Domain;
NCIt definition : A Substrate Domain is a protein region that physically interacts stereospecifically,
and usually at high affinity, with a specific target substrate. In enzymes, the substrate
domain is often, though not necessarily, coincident with the catalytic domain. Typically,
substrate interaction results in some protein conformational alteration and functional
modification. (NCI);
Origin ID : C14073;
UMLS CUI : C1515032;
Associated anatomy of gene products
- Semantic type(s)
- is_structural_domain_or_motif_of_gene_product
