Casein Kinase I Isoform Alpha

Preferred Label : Casein Kinase I Isoform Alpha;

NCIt synonyms : CKI-Alpha; Down-Regulated In Lung Cancer; Casein Kinase I, Alpha Isoform; CSNK1A1; EC 2.7.11.1; CK1; Casein Kinase 1, Alpha 1; Casein Kinase 1 Alpha-1;

NCIt definition : Casein kinase I isoform alpha (337 aa, 39 kDa) is encoded by the human CSNK1A1 gene. This protein plays a role in both protein phosphorylation and receptor-mediated signaling.;

Details

Origin ID

C26033;

UMLS CUI

C1332857;

OMIM relation
- Casein kinase I, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CSNK1A1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CSNK1A1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Hypoxia Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Noncanonical Wnt Signaling Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- CK1 Alpha Degrader CC-91633 [NCIt concept]
- CK1 Alpha Degrader GLB-001 [NCIt concept]
- CK1alpha/CDK7/CDK9 Inhibitor BTX-A51 [NCIt concept]

Keyword's position in hierarchy(ies) :

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