NCIt definition : Encoded by Kinase Family Genes, Kinase enzymes covalently transfer the terminal, gamma
phosphate group from ATP to a variety of substrates and typically play key regulatory
roles in diverse cellular functions. (NCI);
Alternative definition : NCI-GLOSS: A type of enzyme that causes other molecules in the cell to become active.
Some kinases work by adding chemicals called phosphates to other molecules, such as
sugars or proteins. Kinases are a part of many cell processes. Some cancer treatments
target certain kinases that are linked to cancer.;