Hexokinase-1 - CISMeF

Preferred Label : Hexokinase-1;

NCIt synonyms : Hexokinase Type I; HK I; HK1; EC 2.7.1.1; Hexokinase 1; Brain Form Hexokinase; Hexokinase-A;

NCIt definition : Hexokinase-1 (917 aa, 102 kDa) is encoded by the human HK1 gene. This protein is involved in the recognition of bacterial peptidoglycans and the synthesis of hexose-6-phosphates.;

NCIt note : The canonical form of hexokinase-1 is ubiquitously expressed but there are at least 3 additional isoforms, which are encoded by alternatively spliced transcripts and exhibit tissue-specific expression patterns. (EntrezGene and UniProt);

Details

Origin ID

C201739;

OMIM relation
- Hexokinase 1 [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Outer Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Hexokinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amino and Nucleotide Sugars Metabolism Pathway [NCIt concept]
- Butirosin and Neomycin Biosynthesis Pathway [NCIt concept]
- Fructose and Mannose Metabolism Pathway [NCIt concept]
- Galactose Metabolism Pathway [NCIt concept]
- Glycolysis/Gluconeogenesis Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycolysis [NCIt concept]
- Immunity [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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