" /> Glycolysis/Gluconeogenesis Pathway - CISMeF





Preferred Label : Glycolysis/Gluconeogenesis Pathway;

NCIt synonyms : Glycolysis Gluconeogenesis Pathway;

NCIt related terms : Glycolysis / Gluconeogenesis;

Alternative definition : KEGG: Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module, which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from non-carbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths.;

KEGG ID : hsa00010;

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30/07/2025


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