Hexokinase-4 - CISMeF

Preferred Label : Hexokinase-4;

NCIt synonyms : Hexokinase-D; GCK; HK4; Hexokinase D; Glucokinase; EC 2.7.1.1; HK IV; Hexokinase Type IV; Hexokinase 4;

NCIt definition : Hexokinase-4 (465 aa, 52 kDa) is encoded by the human GCK gene. This protein plays a role in the synthesis of hexose-6-phosphates.;

NCI Metathesaurus CUI : CL1920906;

Details

Origin ID

C201645;

UMLS CUI

C5890880;

OMIM relation
- Glucokinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GCK Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Mitochondrion [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Hexokinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amino and Nucleotide Sugars Metabolism Pathway [NCIt concept]
- Butirosin and Neomycin Biosynthesis Pathway [NCIt concept]
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
- Galactose Metabolism Pathway [NCIt concept]
- Glycolysis/Gluconeogenesis Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Glycogenesis Induction [NCIt concept]
- Glycolysis [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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