Pyruvate Kinase PKLR

Preferred Label : Pyruvate Kinase PKLR;

NCIt synonyms : Pyruvate Kinase 1; EC 2.7.1.40; R-Type Pyruvate Kinase; Pyruvate Kinase PKR; PKR; PKLR; Pyruvate Kinase PKLR Isoform R-Type; R-Type PK; Pyruvate Kinase L/R; Pyruvate Kinase Isozymes R/L; Pyruvate Kinase Isozymes L/R; Red Cell Pyruvate Kinase; Pyruvate Kinase R; Pyruvate Kinase Isozymes R; R-Type/L-Type Pyruvate Kinase; Red Cell/Liver Pyruvate Kinase; Pyruvate Kinase Isozyme R/L; Pyruvate Kinase Isozyme R;

NCIt definition : Pyruvate kinase PKLR (574 aa, 62 kDa) is encoded by the human PKLR gene. This protein plays a role in the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP in erythrocytes.;

NCIt note : UniProt considers isoform R the canonical form of the pyruvate kinase PKLR protein.;

NCI Metathesaurus CUI : CL936914;

Détails

Origin ID

C157139;

UMLS CUI

C4760813;

Automatic exact mappings (from CISMeF team)
- Eukaryotic translation initiation factor 2-alpha kinase 2 [OMIM gene]
- Pyruvate kinase, liver and red blood cell [OMIM gene]
- R-Type pyruvate kinase [MeSH concept]
- polycystic kidney diseases [MeSH Descriptor]
- pyruvate kinase [MeSH Descriptor]
- pyruvate kinase L/R [ORDO Gene]
- pyruvate kinase L/R [HGNC gene]
OMIM relation
- Pyruvate kinase, liver and red blood cell [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PKLR Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Erythrocyte [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Pyruvate Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
- Glycolysis/Gluconeogenesis Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Glycolysis [NCIt concept]
- Phosphorylation Process [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients