pyruvate kinase

Preferred Label : pyruvate kinase;

MeSH definition : ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.;

MeSH hyponym : M1-Type pyruvate kinase; pyruvate kinase L; R-Type pyruvate kinase; M-Type pyruvate kinase; M2-Type pyruvate kinase; L-Type Pyruvate Kinase; L Type Pyruvate Kinase; Pyruvate Kinase, L-Type; M1 Type Pyruvate Kinase; Pyruvate Kinase, M1-Type; M Type Pyruvate Kinase; Pyruvate Kinase, M-Type; M2 Type Pyruvate Kinase; Pyruvate Kinase, M2-Type; Pyruvate Kinase, R-Type; R Type Pyruvate Kinase;

MeSH Related Number : 9001-59-6 (CAS RN);

Registry Number MeSH : EC 2.7.1.40;

MeSH annotation : do not coord L-, R-, M-, M1- or M2-type pyruvate kinase with ISOENZYMES;

Wikipedia link : https://en.wikipedia.org/wiki/Pyruvate kinase;

Is substance : O;

UNII : EC 2.7.1.40;

Details

Origin ID

D011770;

UMLS CUI

C0034348;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Pyruvate Kinase [NCIt concept]
- Pyruvate Kinase Measurement [NCIt concept]
- Pyruvate kinase [MedDRA Preferred Term]
- Pyruvate kinase [LOINC component]
- Pyruvate kinase (substance) [SNOMED CT concept]
- pyruvate kinase [SNOMED Notion]
Indexing information
- 4-((1,1-dioxo-1,2-benzothiazol-3-yl)sulfanyl)benzoic acid [MeSH Supplementary Concept]
- SGI-10067 [MeSH Supplementary Concept]
- SGI-9380 [MeSH Supplementary Concept]
- thyroid hormone-binding proteins [MeSH Supplementary Concept]
Record concept(s)
- M-Type pyruvate kinase [MeSH concept]
- M1-Type pyruvate kinase [MeSH concept]
- M2-Type pyruvate kinase [MeSH concept]
- R-Type pyruvate kinase [MeSH concept]
- pyruvate kinase [MeSH concept]
- pyruvate kinase L [MeSH concept]
Related MeSH Supplementary Concept(s)
- Cdc19 protein, S cerevisiae [MeSH Supplementary Concept]
- PKLR protein, human [MeSH Supplementary Concept]
- PKM2 protein, human [MeSH Supplementary Concept]
- Pklr protein, mouse [MeSH Supplementary Concept]
- Pkm protein, mouse [MeSH Supplementary Concept]
- Pkm protein, rat [MeSH Supplementary Concept]
- pyruvate kinase deficiency of red cells [MeSH Supplementary Concept]
- pyruvate kinase mallorca [MeSH Supplementary Concept]
See also
- anemia, hemolytic [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Pyruvate Kinase [NCIt concept]
- Pyruvate kinase [LOINC part]
- Pyruvate kinase [LOINC component]
- Pyruvate kinase (substance) [SNOMED CT concept]
- pyruvate kinase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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