Gamma-Enolase - CISMeF

Preferred Label : Gamma-Enolase;

NCIt synonyms : Neuron-Specific Enolase; Enolase 2; Phosphopyruvate Hydratase; EC 4.2.1.11; Neural Enolase; 2-Phospho-D-Glycerate Hydro-Lyase; ENO2;

NCIt related terms : NSE;

NCIt definition : Gamma-enolase (434 aa, 47 kDa) is encoded by the human ENO2 gene. This protein is involved in glycolysis, neurotrophy and neuroprotection.;

NCIt note : Gamma-enolase is expressed specifically in neurons.; Gamma-enolase protein levels are significantly elevated in brain tumors and Creutzfeld-Jacob disease. Cardiovascular accidents and cerebral trauma also cause dramatic increases in levels of this protein.;

Details

Origin ID

C62216;

UMLS CUI

C5441659;

Automatic exact mappings (from CISMeF team)
- ENO1 protein, S cerevisiae [MeSH Supplementary Concept]
- ENO1 protein, human [MeSH Supplementary Concept]
- Eno1 protein, mouse [MeSH Supplementary Concept]
- Enolase 1 [OMIM gene]
- Enolase 2 [OMIM gene]
- Neuron-specific enolase [MedDRA LLT]
- Neurone-specific enolase [MedDRA Preferred Term]
- alpha-enolase P46, bacteroides fragilis [MeSH Supplementary Concept]
- alpha-enolase, onchocerca volvulus [MeSH Supplementary Concept]
- enolase 2 [HGNC gene]
- enolase 2, S cerevisiae [MeSH Supplementary Concept]
- enolase 2, zebrafish [MeSH Supplementary Concept]
- glycogen synthase [MeSH Descriptor]
- hydroxymandelonitrile lyase [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Enolase [LOINC component]
- Enolase (substance) [SNOMED CT concept]
- Enolase.neuron specific [LOINC component]
- Gamma-enolase (substance) [SNOMED CT concept]
- gamma-Enolase [MeSH concept]
- neuron-specific enolase [SNOMED Notion]
- phosphopyruvate hydratase [MeSH Descriptor]
- phosphopyruvate hydratase [MeSH concept]
OMIM relation
- Enolase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ENO2 protein, human [MeSH Supplementary Concept]
- Enolase.neuron specific [LOINC component]
- Gamma-enolase (substance) [SNOMED CT concept]
- gamma-Enolase [MeSH concept]
- neuron-specific enolase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- EWS Authorized Value Terminology [NCIt concept]
- EWS Immunohistochemistry Table [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- ENO2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_of
- Lung Small Cell Carcinoma [NCIt concept]
- Neuroendocrine Carcinoma [NCIt concept]
gene_product_is_element_in_pathway
- Glycolysis Pathway [NCIt concept]
- Glycolysis/Gluconeogenesis Pathway [NCIt concept]
- RNA Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Survival [NCIt concept]

Keyword's position in hierarchy(ies) :

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