Alcohol Dehydrogenase Class-3

Preferred Label : Alcohol Dehydrogenase Class-3;

NCIt synonyms : ADH5; Glutathione-Dependent Formaldehyde Dehydrogenase; Alcohol Dehydrogenase Class-III; Formaldehyde Dehydrogenase; FALDH; EC 1.1.1.284; Alcohol Dehydrogenase 5; EC 1.1.1.1; GSH-FDH; S-(Hydroxymethyl)Glutathione Dehydrogenase; Alcohol Dehydrogenase Class Chi Chain; FDH;

NCIt definition : Alcohol dehydrogenase class-3 (374 aa, 40 kDa) is encoded by the human ADH5 gene. This protein plays a role in the oxidation of long-chain primary alcohols, long chain omega-hydroxy fatty acids and the formaldehyde adduct, S-(hydroxymethyl) glutathione.;

Details

Origin ID

C213900;

OMIM relation
- Alcohol dehydrogenase 5, chi polypeptide [OMIM gene]
gene_encodes_gene_product
- ADH5 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Alcohol Dehydrogenase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- Glycolysis/Gluconeogenesis Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
- Tyrosine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Detoxification [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Histogenic Process [NCIt concept]
- Nervous System Development [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

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