Detoxification

Preferred Label : Detoxification;

NCIt synonyms : Metabolism of Toxic Agents; Detoxification Process;

NCIt related terms : detoxify;

NCIt definition : A process to transform a substance with pharmacologic or toxic activities into an alternative form with reduced activity or which can be cleared from the organism more quickly.;

Alternative definition : NCI-GLOSS: To make something less poisonous or harmful. It may refer to the process of removing toxins, poisons, or other harmful substances from the body.;

Codes from synonyms : CDR0000446105;

Details

Origin ID

C16841;

UMLS CUI

C0025516;

Automatic exact mappings (from CISMeF team)
- Detoxification [HPMULTI term]
- Detoxification [ICHI action]
- detoxification [GO term]
Currated CISMeF NLP mapping
- Detoxification [MedDRA Preferred Term]
- Detoxification NOS [MedDRA LLT]
- Detoxification therapy (regime/therapy) [SNOMED CT concept]
- detoxification [IUPAC Term]
Semantic type(s)
- Organism Function [UMLS semantic type]
UMLS correspondences (same concept)
- detoxification [GO term]
- metabolic detoxication, drug [MeSH concept]
biological_process_involves_gene_product
- 1,25-Dihydroxyvitamin D(3) 24-Hydroxylase, Mitochondrial [NCIt concept]
- 24-Hydroxycholesterol 7-Alpha-Hydroxylase [NCIt concept]
- 25-Hydroxycholesterol 7-Alpha-Hydroxylase [NCIt concept]
- 25-Hydroxyvitamin D-1 Alpha-Hydroxylase, Mitochondrial [NCIt concept]
- 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase [NCIt concept]
- Aflatoxin B1 Aldehyde Reductase Member 2 [NCIt concept]
- Aldehyde Dehydrogenase [NCIt concept]
- Aldehyde Dehydrogenase 1 Family [NCIt concept]
- Aldehyde Dehydrogenase 3 Family [NCIt concept]
- Argininosuccinate Lyase [NCIt concept]
- Aromatase [NCIt concept]
- Arylamine N-Acetyltransferase 1 [NCIt concept]
- Arylamine N-Acetyltransferase 2 [NCIt concept]
- Carbamoyl-Phosphate Synthase [Ammonia], Mitochondrial [NCIt concept]
- Catalase [NCIt concept]
- Chloramphenicol O-acetyltransferase [NCIt concept]
- Cholesterol 7-Alpha-Monooxygenase [NCIt concept]
- Cholesterol Side-Chain Cleavage Enzyme, Mitochondrial [NCIt concept]
- Cholinesterase [NCIt concept]
- Cystathionine Beta-Synthase [NCIt concept]
- Cytochrome P450 [NCIt concept]
- Cytochrome P450 11B2, Mitochondrial [NCIt concept]
- Cytochrome P450 1A1 [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 1B1 [NCIt concept]
- Cytochrome P450 26A1 [NCIt concept]
- Cytochrome P450 26B1 [NCIt concept]
- Cytochrome P450 2A13 [NCIt concept]
- Cytochrome P450 2A6 [NCIt concept]
- Cytochrome P450 2A7 [NCIt concept]
- Cytochrome P450 2B6 [NCIt concept]
- Cytochrome P450 2C18 [NCIt concept]
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 2C8 [NCIt concept]
- Cytochrome P450 2C9 [NCIt concept]
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 2E1 [NCIt concept]
- Cytochrome P450 2U1 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
- Cytochrome P450 4V2 [NCIt concept]
- Cytochrome P450 CYP11B1, Mitochondrial [NCIt concept]
- Epoxide Hydrolase 1 [NCIt concept]
- Extracellular Superoxide Dismutase [Cu-Zn] [NCIt concept]
- Glutamate-Cysteine Ligase Catalytic Subunit [NCIt concept]
- Glutamate-Cysteine Ligase Regulatory Subunit [NCIt concept]
- Glutathione Peroxidase 1 [NCIt concept]
- Glutathione Peroxidase 2 [NCIt concept]
- Glutathione Peroxidase 3 [NCIt concept]
- Glutathione S-Transferase Alpha [NCIt concept]
- Glutathione S-Transferase Mu [NCIt concept]
- Glutathione S-Transferase Mu 1 [NCIt concept]
- Glutathione S-Transferase Mu 3 [NCIt concept]
- Glutathione S-Transferase Mu 4 [NCIt concept]
- Glutathione S-Transferase P [NCIt concept]
- Glutathione S-Transferase Theta-1 [NCIt concept]
- Glutathione S-Transferase Theta-2 [NCIt concept]
- NAD(P)H Dehydrogenase [Quinone] 1 [NCIt concept]
- Nuclear Receptor Subfamily 1 Group I Member 2 [NCIt concept]
- Nuclear Receptor Subfamily 1 Group I Member 3 [NCIt concept]
- Nucleotide Triphosphate Diphosphatase NUDT15 [NCIt concept]
- Oxidized Purine Nucleoside Triphosphate Hydrolase [NCIt concept]
- Serum Paraoxonase/Arylesterase 1 [NCIt concept]
- Steroid 17-Alpha-Hydroxylase/17,20 Lyase [NCIt concept]
- Steroid 21-Hydroxylase [NCIt concept]
- Sterol 26-Hydroxylase, Mitochondrial [NCIt concept]
- Superoxide Dismutase [Cu-Zn] [NCIt concept]
- Superoxide Dismutase [Mn], Mitochondrial [NCIt concept]
- UDP-Glucuronosyltransferase 1-7 [NCIt concept]
- UDP-Glucuronosyltransferase 1-9 [NCIt concept]
- Valacyclovir Hydrolase [NCIt concept]
- Vitamin D 25-Hydroxylase [NCIt concept]
biological_process_is_part_of_process
- Host Defense Mechanism [NCIt concept]
- Resistance Process [NCIt concept]
biological_process_results_from_biological_process
- Oxidative Stress [NCIt concept]
process_involves_gene
- AKR7A2 Gene [NCIt concept]
- AKR7A2 wt Allele [NCIt concept]
- ASL Gene [NCIt concept]
- ASL wt Allele [NCIt concept]
- BCHE Gene [NCIt concept]
- BCHE wt Allele [NCIt concept]
- CAT Gene [NCIt concept]
- CAT wt Allele [NCIt concept]
- CBS Gene [NCIt concept]
- CBS wt Allele [NCIt concept]
- CPS1 Gene [NCIt concept]
- CPS1 wt Allele [NCIt concept]
- CYP11A1 Gene [NCIt concept]
- CYP11A1 wt Allele [NCIt concept]
- CYP11B1 Gene [NCIt concept]
- CYP11B1 wt Allele [NCIt concept]
- CYP11B2 Gene [NCIt concept]
- CYP11B2 wt Allele [NCIt concept]
- CYP17A1 Gene [NCIt concept]
- CYP17A1 wt Allele [NCIt concept]
- CYP19A1 Gene [NCIt concept]
- CYP19A1 wt Allele [NCIt concept]
- CYP1A1 Gene [NCIt concept]
- CYP1A1 wt Allele [NCIt concept]
- CYP1A2 Gene [NCIt concept]
- CYP1A2 wt Allele [NCIt concept]
- CYP1A2*1 Allele [NCIt concept]
- CYP1A2*11 Allele [NCIt concept]
- CYP1A2*7 Allele [NCIt concept]
- CYP1B1 Gene [NCIt concept]
- CYP1B1 wt Allele [NCIt concept]
- CYP21A2 Gene [NCIt concept]
- CYP21A2 wt Allele [NCIt concept]
- CYP24A1 Gene [NCIt concept]
- CYP24A1 wt Allele [NCIt concept]
- CYP26A1 Gene [NCIt concept]
- CYP26A1 wt Allele [NCIt concept]
- CYP26B1 Gene [NCIt concept]
- CYP26B1 wt Allele [NCIt concept]
- CYP27A1 Gene [NCIt concept]
- CYP27A1 wt Allele [NCIt concept]
- CYP27B1 Gene [NCIt concept]
- CYP27B1 wt Allele [NCIt concept]
- CYP2A13 Gene [NCIt concept]
- CYP2A13 wt Allele [NCIt concept]
- CYP2A6 Gene [NCIt concept]
- CYP2A6 wt Allele [NCIt concept]
- CYP2A7 Gene [NCIt concept]
- CYP2A7 wt Allele [NCIt concept]
- CYP2B6 Gene [NCIt concept]
- CYP2B6 wt Allele [NCIt concept]
- CYP2C18 Gene [NCIt concept]
- CYP2C18 wt Allele [NCIt concept]
- CYP2C19 Gene [NCIt concept]
- CYP2C19 wt Allele [NCIt concept]
- CYP2C19*1 Allele [NCIt concept]
- CYP2C19*10 Allele [NCIt concept]
- CYP2C19*12 Allele [NCIt concept]
- CYP2C19*2 Allele [NCIt concept]
- CYP2C19*3 Allele [NCIt concept]
- CYP2C19*4 Allele [NCIt concept]
- CYP2C19*5 Allele [NCIt concept]
- CYP2C19*6 Allele [NCIt concept]
- CYP2C19*7 Allele [NCIt concept]
- CYP2C19*8 Allele [NCIt concept]
- CYP2C19*9 Allele [NCIt concept]
- CYP2C8 Gene [NCIt concept]
- CYP2C8 wt Allele [NCIt concept]
- CYP2C8*2 Allele [NCIt concept]
- CYP2C8*3 Allele [NCIt concept]
- CYP2C8*4 Allele [NCIt concept]
- CYP2C8*5 Allele [NCIt concept]
- CYP2C8*6 Allele [NCIt concept]
- CYP2C8*7 Allele [NCIt concept]
- CYP2C8*8 Allele [NCIt concept]
- CYP2C9 Gene [NCIt concept]
- CYP2C9 wt Allele [NCIt concept]
- CYP2C9*1 Allele [NCIt concept]
- CYP2C9*11 Allele [NCIt concept]
- CYP2C9*12 Allele [NCIt concept]
- CYP2C9*16 Allele [NCIt concept]
- CYP2C9*18 Allele [NCIt concept]
- CYP2C9*2 Allele [NCIt concept]
- CYP2C9*3 Allele [NCIt concept]
- CYP2C9*5 Allele [NCIt concept]
- CYP2C9*6 Allele [NCIt concept]
- CYP2C9*8 Allele [NCIt concept]
- CYP2D6 Gene [NCIt concept]
- CYP2D6 wt Allele [NCIt concept]
- CYP2D6*1 Allele [NCIt concept]
- CYP2D6*10 Allele [NCIt concept]
- CYP2D6*11 Allele [NCIt concept]
- CYP2D6*12 Allele [NCIt concept]
- CYP2D6*13 Allele [NCIt concept]
- CYP2D6*14 Allele [NCIt concept]
- CYP2D6*15 Allele [NCIt concept]
- CYP2D6*16 Allele [NCIt concept]
- CYP2D6*17 Allele [NCIt concept]
- CYP2D6*18 Allele [NCIt concept]
- CYP2D6*19 Allele [NCIt concept]
- CYP2D6*2 Allele [NCIt concept]
- CYP2D6*20 Allele [NCIt concept]
- CYP2D6*21 Allele [NCIt concept]
- CYP2D6*2N Allele [NCIt concept]
- CYP2D6*3 Allele [NCIt concept]
- CYP2D6*35X2 Allele [NCIt concept]
- CYP2D6*36 Allele [NCIt concept]
- CYP2D6*38 Allele [NCIt concept]
- CYP2D6*4 Allele [NCIt concept]
- CYP2D6*40 Allele [NCIt concept]
- CYP2D6*41 Allele [NCIt concept]
- CYP2D6*42 Allele [NCIt concept]
- CYP2D6*44 Allele [NCIt concept]
- CYP2D6*5 Allele [NCIt concept]
- CYP2D6*6 Allele [NCIt concept]
- CYP2D6*7 Allele [NCIt concept]
- CYP2D6*8 Allele [NCIt concept]
- CYP2D6*9 Allele [NCIt concept]
- CYP2E1 Gene [NCIt concept]
- CYP2E1 wt Allele [NCIt concept]
- CYP2E1*1 Allele [NCIt concept]
- CYP2E1*2 Allele [NCIt concept]
- CYP2R1 Gene [NCIt concept]
- CYP2R1 wt Allele [NCIt concept]
- CYP2U1 Gene [NCIt concept]
- CYP2U1 wt Allele [NCIt concept]
- CYP39A1 Gene [NCIt concept]
- CYP39A1 wt Allele [NCIt concept]
- CYP3A Gene Locus [NCIt concept]
- CYP3A4 Gene [NCIt concept]
- CYP3A4 wt Allele [NCIt concept]
- CYP3A4*17 Allele [NCIt concept]
- CYP3A4*18 Allele [NCIt concept]
- CYP3A5 Gene [NCIt concept]
- CYP3A5 wt Allele [NCIt concept]
- CYP3A5*10 Allele [NCIt concept]
- CYP3A5*3 Allele [NCIt concept]
- CYP3A5*6 Allele [NCIt concept]
- CYP3A5*8 Allele [NCIt concept]
- CYP3A5*9 Allele [NCIt concept]
- CYP3A7 Gene [NCIt concept]
- CYP3A7 wt Allele [NCIt concept]
- CYP3A7*2 Allele [NCIt concept]
- CYP4V2 Gene [NCIt concept]
- CYP4V2 wt Allele [NCIt concept]
- CYP7A1 Gene [NCIt concept]
- CYP7A1 wt Allele [NCIt concept]
- CYP7B1 Gene [NCIt concept]
- CYP7B1 wt Allele [NCIt concept]
- CYP8B1 Gene [NCIt concept]
- CYP8B1 wt Allele [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- EPHX1 Gene [NCIt concept]
- EPHX1 wt Allele [NCIt concept]
- GCLC Gene [NCIt concept]
- GCLC wt Allele [NCIt concept]
- GCLM Gene [NCIt concept]
- GCLM wt Allele [NCIt concept]
- GPX1 Gene [NCIt concept]
- GPX1 wt Allele [NCIt concept]
- GPX2 Gene [NCIt concept]
- GPX2 wt Allele [NCIt concept]
- GPX3 Gene [NCIt concept]
- GPX3 wt Allele [NCIt concept]
- GSTM1 Gene [NCIt concept]
- GSTM1 wt Allele [NCIt concept]
- GSTM3 Gene [NCIt concept]
- GSTM3 wt Allele [NCIt concept]
- GSTM4 Gene [NCIt concept]
- GSTM4 wt Allele [NCIt concept]
- GSTP1 Gene [NCIt concept]
- GSTP1 wt Allele [NCIt concept]
- GSTT1 Gene [NCIt concept]
- GSTT1 wt Allele [NCIt concept]
- GSTT2 Gene [NCIt concept]
- GSTT2 wt Allele [NCIt concept]
- NAT1 Gene [NCIt concept]
- NAT1 wt Allele [NCIt concept]
- NAT2 Gene [NCIt concept]
- NAT2 wt Allele [NCIt concept]
- NAT2*14 Allele [NCIt concept]
- NAT2*5 Allele [NCIt concept]
- NAT2*6 Allele [NCIt concept]
- NAT2*7 Allele [NCIt concept]
- NQO1 Gene [NCIt concept]
- NQO1 wt Allele [NCIt concept]
- NQO1*2 Allele [NCIt concept]
- NR1I2 Gene [NCIt concept]
- NR1I2 wt Allele [NCIt concept]
- NR1I3 Gene [NCIt concept]
- NR1I3 wt Allele [NCIt concept]
- NUDT1 Gene [NCIt concept]
- NUDT1 wt Allele [NCIt concept]
- NUDT15 Gene [NCIt concept]
- NUDT15 wt Allele [NCIt concept]
- PON1 Gene [NCIt concept]
- PON1 wt Allele [NCIt concept]
- SOD1 Gene [NCIt concept]
- SOD1 wt Allele [NCIt concept]
- SOD2 Gene [NCIt concept]
- SOD2 wt Allele [NCIt concept]
- SOD3 Gene [NCIt concept]
- SOD3 wt Allele [NCIt concept]
- UGT1A7 Gene [NCIt concept]
- UGT1A7 wt Allele [NCIt concept]
- UGT1A9 Gene [NCIt concept]
- UGT1A9 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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