2'-5'-Oligoadenylate Synthase 1

Preferred Label : 2'-5'-Oligoadenylate Synthase 1;

NCIt synonyms : OAS1; 2-5A Synthetase 1; p46/p42 OAS; 2'-5' Oligoadenylate Synthase 1; 2'-5'-Oligoadenylate Synthetase 1; (2-5')Oligo(A) Synthase 1; 2'-5'-Oligoisoadenylate Synthetase 1; 2-5A Synthase 1; E18/E16; 2',5'-Oligo A Synthetase 1; EC 2.7.7.84;

NCIt definition : 2'-5'-oligoadenylate synthase 1 (400 aa, 46 kDa) is encoded by the human OAS1 gene. This protein plays a role in antiviral activity.;

Details

Origin ID

C185109;

UMLS CUI

C1259226;

Automatic exact mappings (from CISMeF team)
- 2'-5'-oligoadenylate synthetase 1 [ORDO Gene]
- 2'-5'-oligoadenylate synthetase 1 [HGNC gene]
- 2-prime,5-prime-oligoadenylate synthetase 1 [OMIM gene]
OMIM relation
- 2-prime,5-prime-oligoadenylate synthetase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- OAS1 protein, human [MeSH Supplementary Concept]
- OAS1 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- OAS1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
- Extracellular Space [NCIt concept]
- Mitochondrion [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- NOD-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Degradation [NCIt concept]

Keyword's position in hierarchy(ies) :

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