Tyrosine-Protein Kinase Lck

Preferred Label : Tyrosine-Protein Kinase Lck;

NCIt synonyms : T Cell-Specific Protein-Tyrosine Kinase; Proto-Oncogene Tyrosine-Protein Kinase LCK; LSK; P56-LCK; EC 2.7.1.112; Lymphocyte-Specific Protein-Tyrosine Kinase; Lymphocyte-Specific Protein Tyrosine Kinase; T-Cell Specific Protein Tyrosine Kinase; Lymphocyte-Specific p56LCK Tyrosine Protein Kinase; LCK; EC 2.7.10.2; Leukocyte C-Terminal Src Kinase; Protein YT16; Proto-Oncogene Lck; Lymphocyte Cell-Specific Protein-Tyrosine Kinase;

NCIt definition : Tyrosine-protein kinase Lck (509 aa, 58 kDa) is encoded by the human LCK gene. This protein is involved in tyrosine phosphorylation, T-cell maturation and ligand-dependent signaling.;

Details

Origin ID

C17309;

UMLS CUI

C3853652;

OMIM relation
- Lck protooncogene, src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- LCK Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- T-Cell Apoptosis Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TCR Activation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Activation [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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