2'-5'-Oligoadenylate Synthase 2

Preferred Label : 2'-5'-Oligoadenylate Synthase 2;

NCIt synonyms : P69 OAS / P71 OAS; OAS2; p69; (2'-5')Oligo(A) Synthetase 2; 2'-5'-Oligoadenylate Synthetase 2; (2-5')Oligo(A) Synthase 2; P69OAS / P71OAS; 2-5A Synthase 2; EC 2.7.7.84;

NCIt definition : 2'-5'-oligoadenylate synthase 2 (719 aa, 82 kDa) is encoded by the human OAS2 gene. This protein plays a role in interferon-induced degradation of double stranded viral RNA by RNAse L.;

Details

Origin ID

C175372;

UMLS CUI

C5444782;

Automatic exact mappings (from CISMeF team)
- 2'-5'-oligoadenylate synthetase 2 [HGNC gene]
- 2-prime,5-prime-oligoadenylate synthetase 2 [OMIM gene]
OMIM relation
- 2-prime,5-prime-oligoadenylate synthetase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- OAS2 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- NOD-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Phosphorylation Process [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Degradation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients