NCIt synonyms : ACTR-IIB; ACVR2B; Activin Receptor Type IIB; EC 2.7.11.30; Activin A Type IIB Receptor; Activin-A Type-IIB Receptor;
NCIt definition : Activin receptor type-2B (512 aa, 58 kDa) is encoded by the human ACVR2B gene. This
protein plays a role in protein kinase-dependent signaling and embryonic development.;
NCIt note : Type I receptors are essential for transmembrane signaling and type II receptors are
required for binding ligands and for expression of type I receptors. Type I and II
receptors form a stable complex after ligand binding, resulting in phosphorylation
of type I receptors by type II receptors.;