Preferred Label : Ligand Binding Domain;
NCIt synonyms : Binding Site; Binding Site Domain;
NCIt definition : A Binding Site Domain is a region of protein that physically interacts stereospecifically,
and usually at high affinity, with a specific ligand, substrate, or a specific domain
of some complex target biomolecule, such as a protein, lipid, carbohydrate, or nucleic
acid. Typically, but not necessarily, the interaction results in protein conformational
alteration and functional modification.;
Origin ID : C13671;
UMLS CUI : C0682969;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- False automatic mappings
- Semantic type(s)
- is_structural_domain_or_motif_of_gene_product
