4F2 Cell-Surface Antigen Heavy Chain

Preferred Label : 4F2 Cell-Surface Antigen Heavy Chain;

NCIt synonyms : CD98 Antigen; Antigen Defined By Monoclonal Antibody 4F2; Monoclonal Antibody 44D7 Antigen; 4F2 Heavy Chain Antigen; 4F2hc; Solute Carrier Family 3 Member 2; Lymphocyte Activation Antigen 4F2 Large Subunit; CD98 Heavy Chain; 4F2 Heavy Chain; SLC3A2;

NCIt definition : 4F2 cell-surface antigen heavy chain (630 aa, 68 kDa) is encoded by the human SLC3A2 gene. This protein plays a role in the positive regulation of amino acid transport.;

NCIt note : 4F2 cell-surface antigen heavy chain forms heterodimers with non-glycosylated amino acid transporter light chains (including SLC7A5, SLC7A6, SLCA7A7, SLC7A8, SLC7A10 or SLCA7A11) to form a functional amino acid transporter. (UniProt);

Details

Origin ID

C124117;

UMLS CUI

C2744118;

Automatic exact mappings (from CISMeF team)
- Fusion Regulatory Protein 1, Heavy Chain [MeSH Descriptor]
- Fusion Regulatory Protein-1 [MeSH Descriptor]
- Fusion Regulatory Protein-1 [MeSH concept]
- Solute carrier family 3 (activator of dibasic and neutral amino acid transport), member 2 [OMIM gene]
- solute carrier family 2 member 3 [HGNC gene]
- solute carrier family 2 member 3 [ORDO Gene]
- solute carrier family 3 member 2 [HGNC gene]
OMIM relation
- Solute carrier family 3 (activator of dibasic and neutral amino acid transport), member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- SLC3A2 protein, human [MeSH Supplementary Concept]
- SLC3A2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC3A2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Amino Acid Transporter [NCIt concept]
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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