L-Type Amino Acid Transporter

Preferred Label : L-Type Amino Acid Transporter;

NCIt synonyms : Leucine Type Transporter; LAT;

NCIt definition : A family of heterodimeric protein complexes that mediate the transport of neutral amino acids, including L-leucine. These complexes are comprised of an invariant heavy chain 4F2 cell-surface antigen heavy chain, which is encoded by the SLC3A2 gene, and one of four light chains, large neutral amino acids transporter small subunit 1 (SLC7A5), Y L amino acid transporter 2 (SLC7A6), Y L amino acid transporter 1 (SLC7A7), or large neutral amino acids transporter small subunit 2 (SLC7A8).;

Details

Origin ID

C120483;

UMLS CUI

C4049852;

Automatic exact mappings (from CISMeF team)
- Origin recognition complex, subunit 3 [OMIM gene]
- latrunculin A [MeSH Supplementary Concept]
Biochemical function of gene products
- Large Neutral Amino Acids Transporter Small Subunit 1 [NCIt concept]
- Large Neutral Amino Acids Transporter Small Subunit 2 [NCIt concept]
- Large Neutral Amino Acids Transporter Small Subunit 3 [NCIt concept]
- Large Neutral Amino Acids Transporter Small Subunit 4 [NCIt concept]
False automatic mappings
- Long-Acting thyroid stimulator [MeSH Descriptor]
- Thyroid stimulating immunoglobulins (substance) [SNOMED CT concept]
- withholding treatment [MeSH Descriptor]
See also inter- (CISMeF)
- Linker for activation of t cells [OMIM gene]
- linker for activation of T cells [ORDO Gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- Amino Acid Transporter [NCIt concept]
- Transport Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Transmembrane Transport [NCIt concept]

Keyword's position in hierarchy(ies) :

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