Transient Receptor Potential Cation Channel Subfamily M Member 4

Preferred Label : Transient Receptor Potential Cation Channel Subfamily M Member 4;

NCIt synonyms : Melastatin-4; hTRPM4; LTrpC4; TRPM4; Melastatin 4; Calcium-Activated Non-Selective Cation Channel 1; LTrpC-4; Long Transient Receptor Potential Channel 4;

NCIt definition : Transient receptor potential cation channel subfamily M member 4 (1214 aa, 134 kDa) is encoded by the human TRPM4 gene. This protein plays a role in calcium-activated transmembrane transport of monovalent cations.;

NCIt note : Although the activity of transient receptor potential cation channel subfamily M member 4 is activated by increases in intracellular calcium ion levels, this channel is impermeable to calcium ions. (UniProt);

Details

Origin ID

C201678;

OMIM relation
- Transient receptor potential cation channel, subfamily M, member 4 [OMIM gene]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- TRPM4 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

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