Nuclear Receptor ROR-Alpha

Preferred Label : Nuclear Receptor ROR-Alpha;

NCIt synonyms : RAR-Related Orphan Receptor Alpha; Retinoic Acid Receptor-Related Orphan Receptor Alpha; RORA; NR1F1; ROR-Alpha; Nuclear Receptor RZR-Alpha; RAR-Related Orphan Receptor-A; RZRA; Transcription Factor RZR-Alpha; RAR-Related Orphan Receptor A; Retinoid-Related Orphan Receptor-Alpha; Nuclear Receptor Subfamily 1 Group F Member 1;

NCIt definition : Nuclear receptor ROR-alpha (556 aa, 63 kDa) is encoded by the human RORA gene. This protein is involved in the positive regulation of transcription.;

NCIt note : RORA interacts with nucleoside diphosphate kinase NM23-2, involved in organogenesis and differentiation, as well as with metastasis suppressor NM23-1 gene product.;

Details

Origin ID

C29881;

UMLS CUI

C0284080;

OMIM relation
- Rar-related orphan receptor a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- RORA protein, human [MeSH concept]
- RORA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- RORA Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Circadian Rhythm Pathway KEGG [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Organogenesis [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients