" /> Epithelial Cell Adhesion Molecule - CISMeF





Preferred Label : Epithelial Cell Adhesion Molecule;

NCIt synonyms : Gastrointestinal Tumor-Associated Antigen 2; Membrane Component, Chromosome 4, Surface Marker 1; KSA Glycoprotein; M4S1 Protein; TROP-1; Epithelial Cellular Adhesive Molecule; Epithelial Glycoprotein 40; EGP40; Ep-CAM; GA733-2 Antigen; TACSTD1; KSA; EPCAM; Epithelial Glycoprotein 314; Adenocarcinoma-Associated Antigen; Major Gastrointestinal Tumor-Associated Protein GA733-2; EGP314; KS 1/4 Antigen; CD326; CD326 Antigen; Epithelial Glycoprotein; EGP; Tumor-Associated Calcium Signal Transducer 1; hEGP314; Epithelial Cell Surface Antigen; MOC31; Antigen CD326; Cell Surface Glycoprotein Trop-1; Tumor-Associated Calcium Signal Transducer-1;

NCIt definition : Epithelial cell adhesion molecule (314 aa, 35 kDa) is encoded by the human EPCAM gene. This protein is involved in both cell adhesion and cellular proliferation.;

NCIt note : Ep-CAM is a cell adhesion molecule expressed in epithelial cells and a ligand for leukocyte-associated immunoglobulin-like receptor 1 (LAIR1). Ep-CAM also binds to LAIR2. Ep-CAM may act to prevent an excessive inflammatory response. Over expression of Ep-CAM in breast cancer may be correlated with the histologic grade of the disease and a predictor of poor prognosis. (from OMIM 600718);

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10/07/2025


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