Colorectal Carcinoma

Preferred Label : Colorectal Carcinoma;

NCIt synonyms : Cancer of Large Intestine; Cancer of the Large Bowel; Large Bowel Carcinoma; Carcinoma of the Large Intestine; Carcinoma of the Large Bowel; Carcinoma of Large Bowel; CRC; Large Intestine Carcinoma; Cancer of the Large Intestine; Carcinoma of Large Intestine; Cancer of Large Bowel; Large Intestine Cancer; Large Bowel Cancer;

NCIt related terms : Colorectal cancer, NOS; Colorectal (Colon or Rectal) Cancer; colorectal cancer;

NCIt definition : A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas.;

Alternative definition : NCI-GLOSS: Cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus).;

Neoplastic status : Malignant;

Codes from synonyms : 10010029; CDR0000444983;

Details

Origin ID

C2955;

UMLS CUI

C0009402;

Automatic exact mappings (from CISMeF team)
- Adenocarcinoma of colon [ICD-11 More detail]
- Malignant neoplasms of large intestine [Bloc CIM-11]
- Malignant tumor of large intestine (disorder) [SNOMED CT concept]
- colorectal neoplasms [MeSH Descriptor]
- large intestine cancer [DO Concept]
Currated CISMeF NLP mapping
- Colorectal cancer [PASCAL descriptor]
- Colorectal cancer [MedDRA Preferred Term]
- Colorectal cancer [OMIM Phenotype]
- Colorectal cancer NOS [MedDRA LLT]
- Colorectal carcinoma [PASCAL descriptor]
- Colorectal carcinoma [MedDRA LLT]
- Large intestine carcinoma [MedDRA LLT]
- Malignant neoplasm of colon and/or rectum (disorder) [SNOMED CT concept]
- colo rectal cancer [Artificial nutrition thesaurus concept]
- colorectal cancer [Radlex concept]
- colorectal cancer [DO Concept]
- colorectal cancer [MedlinePlus Topic]
- colorectal carcinoma [DO Concept]
DO Cross reference
- colorectal carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
See also inter- (CISMeF)
- colon cancer [Disease (Nov.)]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Colorectal cancer [MedDRA Preferred Term]
- Colorectal cancer [OMIM Phenotype]
- Colorectal cancer NOS [MedDRA LLT]
- Colorectal carcinoma [MedDRA LLT]
- Colorectal carcinoma [PASCAL descriptor]
- Large intestine carcinoma [MedDRA LLT]
- colorectal cancer [MedlinePlus Topic]
- colorectal carcinoma [DO Concept]
Validated automatic mappings to NTBT
- colorectal cancer [Disease (Nov.)]
associated_with_malfunction_of_gene_product
- Adenine DNA Glycosylase [NCIt concept]
- Antigen Peptide Transporter 1 [NCIt concept]
- Cadherin-1 [NCIt concept]
- Catenin Beta-1 [NCIt concept]
- Cellular Tumor Antigen p53 [NCIt concept]
- Choline Kinase Alpha [NCIt concept]
- Colorectal Mutant Cancer Protein [NCIt concept]
- Epithelial Cell Adhesion Molecule [NCIt concept]
- Platelet-Derived Growth Factor Receptor-Like Protein [NCIt concept]
- Rho GTPase-Activating Protein 7 [NCIt concept]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI CTEP SDC Colorectal Cancer Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- Bevacizumab/Capecitabine Regimen [NCIt concept]
- Bevacizumab/Fluorouracil Bolus/Leucovorin Regimen [NCIt concept]
- Bevacizumab/Irinotecan Regimen [NCIt concept]
- Bolus Fluorouracil/Leucovorin Regimen [NCIt concept]
- CAPOX Regimen [NCIt concept]
- CAPOX-Bevacizumab Regimen [NCIt concept]
- Capecitabine/Cetuximab Regimen [NCIt concept]
- Capecitabine/Panitumumab Regimen [NCIt concept]
- Cetuximab/Irinotecan Regimen [NCIt concept]
- Cetuximab/Irinotecan/Vemurafenib Regimen [NCIt concept]
- FOLFIRI Regimen [NCIt concept]
- FOLFIRI-Bevacizumab Regimen [NCIt concept]
- FOLFIRI-Cetuximab Regimen [NCIt concept]
- FOLFIRI-Panitumumab Regimen [NCIt concept]
- FOLFIRI-Ramucirumab Regimen [NCIt concept]
- FOLFIRI-Ziv-aflibercept Regimen [NCIt concept]
- FOLFOX-4 Regimen [NCIt concept]
- FOLFOX-6 Regimen [NCIt concept]
- FOLFOX-7 Regimen [NCIt concept]
- FOLFOX-Bevacizumab Regimen [NCIt concept]
- FOLFOX-Cetuximab Regimen [NCIt concept]
- FOLFOX-Panitumumab Regimen [NCIt concept]
- FOLFOXIRI Regimen [NCIt concept]
- FOLFOXIRI-Bevacizumab Regimen [NCIt concept]
- FOLFOXIRI-Cetuximab Regimen [NCIt concept]
- FOLFOXIRI-Panitumumab Regimen [NCIt concept]
- FU-LV Regimen [NCIt concept]
- FU-LV-Bevacizumab Regimen [NCIt concept]
- FUOX Regimen [NCIt concept]
- Fluorouracil Infusional/Leucovorin Regimen [NCIt concept]
- IFL Regimen [NCIt concept]
- IFL-Bevacizumab Regimen [NCIt concept]
- IFL-Douillard Regimen [NCIt concept]
- IFL-FOLFIRI Regimen [NCIt concept]
- IROX-Bevacizumab Regimen [NCIt concept]
- Infusional Fluorouracil/Leucovorin/Bevacizumab Regimen [NCIt concept]
- Irinotecan/Panitumumab Regimen [NCIt concept]
- Irinotecan/Panitumumab/Vemurafenib Regimen [NCIt concept]
- Irinotecan/Ramucirumab Regimen [NCIt concept]
- Irinotecan/Ziv-aflibercept Regimen [NCIt concept]
- Modified FOLFOX Regimen [NCIt concept]
- Modified FOLFOX6 Regimen [NCIt concept]
- XELOX Regimen [NCIt concept]
disease_has_associated_disease
- Hereditary Colorectal Cancer Type X [NCIt concept]
- Hereditary Nonpolyposis Colorectal Cancer Syndrome [NCIt concept]
- Lynch 1 Syndrome [NCIt concept]
- Lynch 2 Syndrome [NCIt concept]
- Lynch Syndrome [NCIt concept]
disease_has_associated_gene
- AXIN2 Gene [NCIt concept]
- AXIN2 wt Allele [NCIt concept]
- BAX Gene [NCIt concept]
- BAX wt Allele [NCIt concept]
- CDH1 Gene [NCIt concept]
- CDH1 wt Allele [NCIt concept]
- CHKA Gene [NCIt concept]
- CHKA wt Allele [NCIt concept]
- DCC Gene [NCIt concept]
- DCC wt Allele [NCIt concept]
- EPCAM Gene [NCIt concept]
- EPCAM wt Allele [NCIt concept]
- MCC Gene [NCIt concept]
- MCC wt Allele [NCIt concept]
- MIR124-1 Gene [NCIt concept]
- MIR124-1 wt Allele [NCIt concept]
- MIR126 Gene [NCIt concept]
- MIR126 wt Allele [NCIt concept]
- MIR127 Gene [NCIt concept]
- MIR127 wt Allele [NCIt concept]
- MIR143 Gene [NCIt concept]
- MIR143 wt Allele [NCIt concept]
- MIR145 Gene [NCIt concept]
- MIR145 wt Allele [NCIt concept]
- MIR17 Gene [NCIt concept]
- MIR17 wt Allele [NCIt concept]
- MIR342 Gene [NCIt concept]
- MIR342 wt Allele [NCIt concept]
- MIR34B Gene [NCIt concept]
- MIR34B wt Allele [NCIt concept]
- MIR34C Gene [NCIt concept]
- MIR34C wt Allele [NCIt concept]
- MIRLET7A1 Gene [NCIt concept]
- MIRLET7A1 wt Allele [NCIt concept]
- MIRLET7A3 Gene [NCIt concept]
- MIRLET7A3 wt Allele [NCIt concept]
- Oncogene N-RAS [NCIt concept]
- PDGFRL Gene [NCIt concept]
- PDGFRL wt Allele [NCIt concept]
- SMAD2 Gene [NCIt concept]
- SMAD2 wt Allele [NCIt concept]
- TAP1 Gene [NCIt concept]
- TAP1 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Large Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
disease_mapped_to_gene
- APC Gene [NCIt concept]
- BRAF Gene [NCIt concept]
- KRAS Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- KRAS Gene Amplification [NCIt concept]
- MYC Gene Mutation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
has_biomarker_gene
- BRINP1 Gene [NCIt concept]
- BRINP1 wt Allele [NCIt concept]
may_be_associated_disease_of_disease
- Attenuated Familial Adenomatous Polyposis [NCIt concept]
- CHEK2-Associated Li-Fraumeni-Like Syndrome [NCIt concept]
- Familial Adenomatous Polyposis [NCIt concept]
- Gardner Syndrome [NCIt concept]
- Juvenile Polyposis Syndrome [NCIt concept]
- MUTYH-Associated Polyposis [NCIt concept]
- Turcot Syndrome [NCIt concept]
- Turcot Syndrome Type 1 [NCIt concept]
- Turcot Syndrome Type 2 [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]
pathogenesis_of_disease_involves_gene
- APC Gene [NCIt concept]
- APC wt Allele [NCIt concept]
- BRAF Gene [NCIt concept]
- BRAF wt Allele [NCIt concept]
- KRAS Gene [NCIt concept]
- KRAS wt Allele [NCIt concept]
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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