Antigen Peptide Transporter 1

Preferred Label : Antigen Peptide Transporter 1;

NCIt synonyms : TAP1; ABC Transporter, MHC 1; APT1; Peptide Supply Factor 1; ATP-Binding Cassette, Sub-Family B, Member 2; Transporter 1, ATP-Binding Cassette, Sub-Family B; Peptide Transporter PSF1; Peptide Transporter TAP1; ATP-Binding Cassette Sub-Family B Member 2; PSF-1; Peptide Transporter Involved In Antigen Processing 1; Transporter Associated With Antigen Processing; ABC Transporter-MHC1; Really Interesting New Gene 4 Protein;

NCIt definition : Antigen peptide transporter 1 (808 aa, 87 kDa) is encoded by the human TAP1 gene. This protein plays a role in cytoplasmic antigen transport and subsequent presentation by MHC class I molecules.;

Details

Origin ID

C21574;

UMLS CUI

C0140599;

OMIM relation
- Transporter, atp-binding cassette, major histocompatibility complex, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TAP1 protein, human [MeSH concept]
- TAP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Multidrug Resistance Gene [NCIt concept]
- TAP1 Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Antigen Presenting Cell [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Permease [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ABC Transporter Pathway [NCIt concept]
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Colorectal Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Processing [NCIt concept]
- Drug Efflux [NCIt concept]
- Immune Surveillance [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Peptide Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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