Antigen Presenting Cell

Preferred Label : Antigen Presenting Cell;

NCIt synonyms : Accessory Cell; Antigen Presenting Cells; Antigen Processing Cell; APC; Antigen-Presenting Cells;

NCIt related terms : antigen-presenting cell;

NCIt definition : A cell that enables a T-lymphocyte to recognize an antigen by engulfing the antigen, breaking down the antigen into smaller fragments which bind to MHC molecules on the surface of the antigen presenting cell. The T-lymphocyte can now recognize and bind with the MHC-linked antigen.;

Alternative definition : NCI-GLOSS: A type of immune cell that boosts immune responses by showing antigens on its surface to other cells of the immune system. An antigen-presenting cell is a type of phagocyte.;

Codes from synonyms : CDR0000044914; CDR0000043977;

Details

Origin ID

C12621;

UMLS CUI

C0003315;

Anatomic structure is physical part of
- Immune System [NCIt concept]
Associated anatomy of gene products
- Protein Unc-93 Homolog B1 [NCIt concept]
Currated CISMeF NLP mapping
- Antigen-Presenting cells [MeSH concept]
- antigen-presenting cells [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- Antigen-Presenting cells [MeSH concept]
- Antigen-presenting cell [FMA entity]
- antigen-presenting cells [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
is_location_of_biological_process
- Antigen Presentation [NCIt concept]
- Antigen Processing [NCIt concept]
- Antigen Sensitization [NCIt concept]
- Human Leukocyte Antigen Sensitization [NCIt concept]
tissue_is_expression_site_of_gene_product
- Antigen Peptide Transporter 1 [NCIt concept]
- Antigen Peptide Transporter 2 [NCIt concept]
- HLA Class II Histocompatibility Antigen, DM Alpha Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DM Beta Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DO Beta Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DQ Alpha 1 Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DR Alpha Chain [NCIt concept]
- HLA-A*02:01/TP53aa264-272 Complex [NCIt concept]
- Peptide/MHC Complex [NCIt concept]

Keyword's position in hierarchy(ies) :

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