HLA Class II Histocompatibility Antigen, DM Beta Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DM Beta Chain;

NCIt synonyms : Really Interesting New Gene 7 Protein; HLA-DM Histocompatibility Type, Beta Chain; Class II Histocompatibility Antigen, M Beta Chain; MHC Class II Antigen HLA-DM Beta Chain; MHC Class II Antigen DMB; MHC Class II HLA-DMB; HLA-DMB;

NCIt definition : HLA class II histocompatibility antigen, DM beta chain (263 aa, 29 kDa) is encoded by the human HLA-DMB gene. This protein is involved in removing the class II-associated invariant chain peptide (CLIP) from newly synthesized class II major histocompatibility protein complexes.;

NCI Metathesaurus CUI : CL551872;

Details

Origin ID

C150056;

UMLS CUI

C4724247;

Automatic exact mappings (from CISMeF team)
- HLA-DM antigens [MeSH Supplementary Concept]
- HLA-DM antigens [MeSH concept]
- Major histocompatibility complex, class II, dm beta [OMIM gene]
- histocompatibility antigens class ii [MeSH Descriptor]
OMIM relation
- Major histocompatibility complex, class II, dm beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- HLA-DMB Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- Antigen Presenting Cell [NCIt concept]
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endosome [NCIt concept]
- Membrane of the Lysosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- HLA Complex [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Peptide/MHC Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Protein Cleavage [NCIt concept]

Keyword's position in hierarchy(ies) :

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