Peptide/MHC Complex

Preferred Label : Peptide/MHC Complex;

NCIt synonyms : Peptide-Major Histocompatibility Protein Complex; Peptide-MHC; pMHC; Peptide MHC Complex;

NCIt definition : Peptide MHC Complexes consist of proteolytically-processed low molecular weight amino acid fragments of antigenic foreign proteins noncovalently bound to self MHC antigens and displayed on the surface of antigen presenting macrophages to helper T cells as an important part of an immune response.;

Details

Origin ID

C18930;

UMLS CUI

C1335376;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
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- Antigen Presenting Cell [NCIt concept]
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- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- T-Cell Activation [NCIt concept]
has_gene_product_element
- HLA Class II Histocompatibility Antigen, DM Alpha Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DM Beta Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DO Beta Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DR Alpha Chain [NCIt concept]

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