HLA Class II Histocompatibility Antigen, DR Alpha Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DR Alpha Chain;

NCIt synonyms : MHC Class II Antigen DRA; Histocompatibility Antigen HLA-DR Alpha;

NCIt definition : HLA class II histocompatibility antigen, DR alpha chain (254 aa, 29 kDa) is encoded by the human HLA-DRA gene. This protein plays a role in the presentation of antigen for recognition by CD4 T-cells.;

Details

Origin ID

C101159;

UMLS CUI

C0019763;

Currated CISMeF NLP mapping
- HLA-DR alpha-Chains [MeSH Descriptor]
OMIM relation
- Major histocompatibility complex, class II, dr alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- HLA-DR alpha-Chains [MeSH concept]
- HLA-DR alpha-Chains [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HLA-DRA Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- Antigen Presenting Cell [NCIt concept]
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- HLA Complex [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- T-Cell Apoptosis Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- TCR Activation Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Peptide/MHC Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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