Protein Cleavage

Preferred Label : Protein Cleavage;

NCIt definition : Protein Cleavage involves hydrolysis by proteolytic enzymes of specific peptide bond(s), forming smaller polypeptides in the target protein during maturation or modification of functional activity.;

NCI Metathesaurus CUI : CL448675;

Details

Origin ID

C41598;

UMLS CUI

C0597304;

Currated CISMeF NLP mapping
- proteolysis [MeSH concept]
- proteolysis [MeSH Descriptor]
- proteolysis [GO term]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- proteolysis [MeSH concept]
- proteolysis [MeSH Descriptor]
- proteolysis [GO term]
biological_process_involves_gene_product
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 2 [NCIt concept]
- Beta-Secretase 1 [NCIt concept]
- Beta-Secretase 2 [NCIt concept]
- Bone Morphogenetic Protein 1 [NCIt concept]
- CAAX Prenyl Protease 2 [NCIt concept]
- Calpain-1 Catalytic Subunit [NCIt concept]
- Calpain-2 Catalytic Subunit [NCIt concept]
- Calpain-3 [NCIt concept]
- Carboxypeptidase A6 [NCIt concept]
- Complement Factor I [NCIt concept]
- Dipeptidyl Peptidase 9 [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 19 [NCIt concept]
- Granzyme A [NCIt concept]
- Granzyme B [NCIt concept]
- HLA Class II Histocompatibility Antigen, DM Alpha Chain [NCIt concept]
- HLA Class II Histocompatibility Antigen, DM Beta Chain [NCIt concept]
- Hepatocyte Growth Factor Activator [NCIt concept]
- Kallikrein-7 [NCIt concept]
- Kell Blood Group Glycoprotein [NCIt concept]
- Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 [NCIt concept]
- Neuroendocrine Convertase 1 [NCIt concept]
- Presequence Protease, Mitochondrial [NCIt concept]
- Proprotein Convertase Subtilisin/Kexin Type 7 [NCIt concept]
- Threonine Aspartase 1 [NCIt concept]
- Tolloid-Like Protein 1 [NCIt concept]
- Ubiquitin Carboxyl-Terminal Hydrolase 1 [NCIt concept]
- Ubiquitin Carboxyl-Terminal Hydrolase 13 [NCIt concept]
- Ubl Carboxyl-Terminal Hydrolase 18 [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
- Post-Translational Regulation [NCIt concept]
process_involves_gene
- ADAM19 Gene [NCIt concept]
- ADAM19 wt Allele [NCIt concept]
- ADAMTS2 Gene [NCIt concept]
- ADAMTS2 wt Allele [NCIt concept]
- BACE1 Gene [NCIt concept]
- BACE1 wt Allele [NCIt concept]
- BACE2 Gene [NCIt concept]
- BACE2 wt Allele [NCIt concept]
- BMP1 Gene [NCIt concept]
- BMP1 wt Allele [NCIt concept]
- CAPN1 Gene [NCIt concept]
- CAPN1 wt Allele [NCIt concept]
- CAPN2 Gene [NCIt concept]
- CAPN2 wt Allele [NCIt concept]
- CAPN3 Gene [NCIt concept]
- CAPN3 wt Allele [NCIt concept]
- CFI Gene [NCIt concept]
- CFI wt Allele [NCIt concept]
- CPA6 Gene [NCIt concept]
- CPA6 wt Allele [NCIt concept]
- DPP9 Gene [NCIt concept]
- DPP9 wt Allele [NCIt concept]
- GZMA Gene [NCIt concept]
- GZMA wt Allele [NCIt concept]
- GZMB Gene [NCIt concept]
- GZMB wt Allele [NCIt concept]
- KEL Gene [NCIt concept]
- KEL wt Allele [NCIt concept]
- KLK7 Gene [NCIt concept]
- KLK7 wt Allele [NCIt concept]
- MALT1 Gene [NCIt concept]
- MALT1 wt Allele [NCIt concept]
- PCSK1 Gene [NCIt concept]
- PCSK1 wt Allele [NCIt concept]
- PCSK7 Gene [NCIt concept]
- PCSK7 wt Allele [NCIt concept]
- PITRM1 Gene [NCIt concept]
- PITRM1 wt Allele [NCIt concept]
- RCE1 Gene [NCIt concept]
- RCE1 wt Allele [NCIt concept]
- TASP1 Gene [NCIt concept]
- TASP1 wt Allele [NCIt concept]
- TLL1 Gene [NCIt concept]
- TLL1 wt Allele [NCIt concept]
- USP1 Gene [NCIt concept]
- USP1 wt Allele [NCIt concept]
- USP13 Gene [NCIt concept]
- USP13 wt Allele [NCIt concept]
- USP18 Gene [NCIt concept]
- USP18 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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