CAPN1 wt Allele

Preferred Label : CAPN1 wt Allele;

NCIt synonyms : muCL; CANP1; Calpain I, Large Subunit Gene; Calpain, Large Polypeptide L1 Gene; Calcium-Activated Neutral Proteinase 1, Catalytic Subunit Gene; CANP; CANPL1; Calpain 1, (Mu/I) Large Subunit wt Allele; muCANP;

NCIt definition : Human CAPN1 wild-type allele is located in the vicinity of 11q13 and is approximately 31 kb in length. This allele, which encodes calpain-1 catalytic subunit protein, plays a role in limited proteolysis of substrates, which modulates cytoskeletal remodeling and signal transduction.;

GenBank Accession Number : X04366;

Details

Origin ID

C123833;

UMLS CUI

C4084783;

Automatic exact mappings (from CISMeF team)
- Calpain 1 [OMIM gene]
- FAM111 trypsin like peptidase B [ORDO Gene]
- calpain 1 [ORDO Gene]
- canes [MeSH Descriptor]
OMIM relation
- Calpain 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q13 [NCIt concept]
gene_is_element_in_pathway
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Calpain-1 Cell Spread Pathway [NCIt concept]
- Calpain-2 Cell Motility Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Extracellular Matrix Degradation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Cleavage [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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