A Disintegrin and Metalloproteinase with Thrombospondin Motifs 2

Preferred Label : A Disintegrin and Metalloproteinase with Thrombospondin Motifs 2;

NCIt synonyms : ADAM-TS 2; PC I-NP; ADAMTS-2; Procollagen N-Endopeptidase; ADAM-TS2; pNPI; EC 3.4.24.14; Procollagen I N-Proteinase; ADAMTS2; ADAM Metallopeptidase with Thrombospondin Type 1 Motif 2; Procollagen I/II Amino Propeptide-Processing Enzyme;

NCIt definition : A disintegrin and metalloproteinase with thrombospondin motifs 2 (1211 aa, 135 kDa) is encoded by the human ADAMTS2 gene. This protein is involved in the maturation of fibrillar procollagen types I-III and type V.;

NCI Metathesaurus CUI : CL599462;

Details

Origin ID

C192022;

UMLS CUI

C4307913;

OMIM relation
- A disintegrin-like and metalloproteinase with thrombospondin type 1 motif, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ADAMTS2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ADAMTS2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
- Peptidase Family M12B [NCIt concept]
gene_product_has_structural_domain_or_motif
- Disintegrin Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Protein Cleavage [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients