Extracellular Matrix

Preferred Label : Extracellular Matrix;

NCIt synonyms : Cell-Extracellular Matrix; ECM;

NCIt definition : The extracellular matrix is a network of fibers that hold cells together. It is found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. It is broken down during normal physiological and disease processes such as bone remodeling, embryogenesis, cancer, and arthritis.;

Details

Origin ID

C13232;

UMLS CUI

C0015350;

Anatomic structure is physical part of
- Extracellular Space [NCIt concept]
Associated anatomy of gene products
- A Disintegrin and Metalloprotease with Thrombospondin Motifs 1 [NCIt concept]
- A Disintegrin and Metalloprotease with Thrombospondin Motifs 9 [NCIt concept]
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 10 [NCIt concept]
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 [NCIt concept]
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 17 [NCIt concept]
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 2 [NCIt concept]
- Alpha-Tectorin [NCIt concept]
- Ameloblastin [NCIt concept]
- Anosmin-1 [NCIt concept]
- Basement Membrane-Specific Heparan Sulfate Proteoglycan Core Protein [NCIt concept]
- Beta Isomer of C-Terminal Telopeptide of Type I Collagen [NCIt concept]
- Biglycan [NCIt concept]
- Bone Morphogenetic Protein 4 [NCIt concept]
- C-Telopeptide of Type I Collagen Generated by Matrix Metalloproteinases [NCIt concept]
- COL18A1 Gene Product [NCIt concept]
- COL3A1 Gene Product [NCIt concept]
- COL4A2 Gene Product [NCIt concept]
- COL4A3 Gene Product [NCIt concept]
- COL6A3 Gene Product [NCIt concept]
- CTX [NCIt concept]
- Canstatin [NCIt concept]
- Cartilage Oligomeric Matrix Protein [NCIt concept]
- Collagen [NCIt concept]
- Collagen Alpha-1(I) Chain [NCIt concept]
- Collagen Alpha-1(II) Chain [NCIt concept]
- Collagen Alpha-1(III) Chain [NCIt concept]
- Collagen Alpha-1(V) Chain [NCIt concept]
- Collagen Alpha-1(VI) Chain [NCIt concept]
- Collagen Alpha-1(VII) Chain [NCIt concept]
- Collagen Alpha-1(VIII) Chain [NCIt concept]
- Collagen Alpha-1(XI) Chain [NCIt concept]
- Collagen Alpha-1(XVII) Chain [NCIt concept]
- Collagen Alpha-1(XVIII) Chain [NCIt concept]
- Collagen Alpha-2(I) Chain [NCIt concept]
- Collagen Alpha-2(IV) Chain [NCIt concept]
- Collagen Alpha-2(V) Chain [NCIt concept]
- Collagen Alpha-2(VI) Chain [NCIt concept]
- Collagen Alpha-2(XI) Chain [NCIt concept]
- Collagen Alpha-3(IV) Chain [NCIt concept]
- Collagen Alpha-3(VI) Chain [NCIt concept]
- Collagen Alpha-5(IV) Chain [NCIt concept]
- Collagen Alpha-6(IV) Chain [NCIt concept]
- Collagen IV [NCIt concept]
- Decorin [NCIt concept]
- Dentin Sialophosphoprotein [NCIt concept]
- EGF-Containing Fibulin-Like Extracellular Matrix Protein 1 [NCIt concept]
- EMILIN-1 [NCIt concept]
- Elafin [NCIt concept]
- Elastin [NCIt concept]
- Endostatin [NCIt concept]
- Endotrophin [NCIt concept]
- Extra Domain B Fibronectin [NCIt concept]
- Extracellular Matrix Organizing Protein FRAS1 [NCIt concept]
- Extracellular Matrix Protein [NCIt concept]
- Extracellular Matrix Protein 1 [NCIt concept]
- FN1 Gene Product [NCIt concept]
- FRAS1-Related Extracellular Matrix Protein 2 [NCIt concept]
- Fibrillin-1 [NCIt concept]
- Fibrillin-2 [NCIt concept]
- Fibrinogen Alpha Chain [NCIt concept]
- Fibromodulin [NCIt concept]
- Fibronectin [NCIt concept]
- Fibulin-2 [NCIt concept]
- Galectin-1 [NCIt concept]
- Heparan Sulfate Proteoglycan [NCIt concept]
- Laminin [NCIt concept]
- Laminin Subunit Alpha-2 [NCIt concept]
- Laminin Subunit Alpha-3 [NCIt concept]
- Laminin Subunit Beta-2 [NCIt concept]
- Laminin Subunit Gamma-2 [NCIt concept]
- Lumican [NCIt concept]
- Lysyl Oxidase Homolog 1 [NCIt concept]
- Matrix Gla Protein [NCIt concept]
- Metalloproteinase Inhibitor 1 [NCIt concept]
- Metalloproteinase Inhibitor 2 [NCIt concept]
- Metalloproteinase Inhibitor 3 [NCIt concept]
- Mucin-4 [NCIt concept]
- Mucin-5AC [NCIt concept]
- Mucin-6 [NCIt concept]
- N-Telopeptide [NCIt concept]
- Nidogen-1 [NCIt concept]
- Nidogen-2 [NCIt concept]
- Osteocalcin [NCIt concept]
- Osteomodulin [NCIt concept]
- Osteopontin [NCIt concept]
- Periostin [NCIt concept]
- Procollagen Type I C-Terminal Peptide [NCIt concept]
- Procollagen Type I N-Terminal Peptide [NCIt concept]
- Protein Wnt-16 [NCIt concept]
- Proteoglycan [NCIt concept]
- Reelin [NCIt concept]
- SPARC [NCIt concept]
- Serpin B5 [NCIt concept]
- Tenascin [NCIt concept]
- Tenascin Family [NCIt concept]
- Tenascin-X [NCIt concept]
- Thrombospondin [NCIt concept]
- Thrombospondin-1 [NCIt concept]
- Thrombospondin-2 [NCIt concept]
- Transforming Growth Factor-Beta-Induced Protein IG-H3 [NCIt concept]
- Tumstatin [NCIt concept]
- Type I Collagen [NCIt concept]
- Type III Procollagen N-Terminal Peptide [NCIt concept]
- Type VII Collagen [NCIt concept]
- Vascular Endothelial Growth Factor A 165 Isoform [NCIt concept]
- Versican Core Protein [NCIt concept]
- Vitronectin [NCIt concept]
- von Willebrand Factor [NCIt concept]
Automatic exact mappings (from CISMeF team)
- External cardiac massage [MedDRA LLT]
- Multimerin 1 [OMIM gene]
- Portion of extracellular matrix [FMA entity]
- obsolete extracellular matrix component [GO term]
- ultrasonography, mammary [MeSH Descriptor]
Contains anatomical structure(s)
- Collagen Fiber [NCIt concept]
- Connective Tissue Fiber [NCIt concept]
- Elastic Fiber [NCIt concept]
- Ground Substance [NCIt concept]
- Reticular Fiber [NCIt concept]
Currated CISMeF NLP mapping
- extracellular matrix [MeSH Descriptor]
- extracellular matrix [MeSH concept]
False automatic mappings
- extracellular matrix [GO term]
Semantic type(s)
- Tissue [UMLS semantic type]
UMLS correspondences (same concept)
- Portion of extracellular matrix [FMA entity]
- extracellular matrix [GO term]
- extracellular matrix [MeSH concept]
- extracellular matrix [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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