Vitronectin - CISMeF

Preferred Label : Vitronectin;

NCIt synonyms : Complement S-Protein; VTN; Somatomedin B; Serum Spreading Factor; Epibolin; V75; Serum-Spreading Factor; S-Protein;

NCIt definition : Vitronectin (478 aa, 54 kDa) is encoded by the human VTN gene. This protein is involved in the modulation of cell-matrix adhesion and cell spreading.;

NCIt note : Somatomedin-B is a 44 amino acid cysteine-rich peptide that is proteolytically released from the N-terminus of vitronectin.; Vitronectin is an extracellular protein that exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. (RefSeq);

Details

Origin ID

C17283;

UMLS CUI

C4281807;

Currated CISMeF NLP mapping
- Vitronectin [LOINC component]
- vitronectin [MeSH Descriptor]
- vitronectin [MeSH concept]
False automatic mappings
- somatomedin B [MeSH concept]
- somatomedin B [MeSH Supplementary Concept]
OMIM relation
- Vitronectin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
- VTN Gene [NCIt concept]
gene_product_expressed_in_tissue
- Plasma [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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