Tumstatin - CISMeF

Preferred Label : Tumstatin;

NCIt synonyms : Collagen IV (Alpha 3) Monomeric NC1 Domain; COL4A3 Monomeric NC1 Domain;

NCIt related terms : Tumstatin (Human Placenta Collagen Type IV alpha3 Chain NC1 Domain);

NCIt definition : Tumstatin (245 aa, 27 kDa) is encoded by the human COL4A3 gene. This protein is involved in the modulation of angiogenesis.;

NCIt note : Tumstatin is a a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain. (UniProt);

Codes from synonyms : 50633;

Details

Origin ID

C90606;

UMLS CUI

C4316931;

Automatic exact mappings (from CISMeF team)
- Collagen, type iv, alpha-3 [OMIM gene]
- collagen type IV alpha 3 chain [ORDO Gene]
- collagen type IV alpha 3 chain [HGNC gene]
- goodpasture antigen [MeSH concept]
- type IV collagen alpha3 chain [MeSH Supplementary Concept]
OMIM relation
- Collagen, type iv, alpha-3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- COL4A3 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Basement Membrane [NCIt concept]
- Extracellular Matrix [NCIt concept]
gene_product_has_biochemical_function
- Angiogenesis Inhibitory Protein [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Morphogenesis [NCIt concept]
- Negative Regulation of Angiogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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