Collagen Alpha-1(XVIII) Chain

Preferred Label : Collagen Alpha-1(XVIII) Chain;

NCIt synonyms : COL18A1; COL18A1 Protein; Collagen, Type XVIII, Alpha 1; Collagen Alpha1 (XVIII); Collagen XVIII (Alpha 1); Collagen XVIII Alpha-1;

NCIt definition : Collagen alpha-1(XVIII) chain (1754 aa, 178 kDa) is encoded by the human COL18A1 gene. This protein is involved in extracellular matrix structure, closure of the neural tube and retinal development.;

NCIt note : The proteolytically produced C-terminal fragment of the collagen alpha-1 (XVIII) chain protein is endostatin, which may be a potent antiangiogenic protein.;

Details

Origin ID

C17792;

UMLS CUI

C4082596;

Automatic exact mappings (from CISMeF team)
- Collagen, type XVIII, alpha-1 [OMIM gene]
- collagen type XVIII [MeSH Descriptor]
- collagen type XVIII alpha 1 chain [ORDO Gene]
- collagen type XVIII, alpha1 subunit [MeSH concept]
OMIM relation
- Collagen, type XVIII, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- COL18A1 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Kidney [NCIt concept]
- Liver [NCIt concept]
- Lung [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Prostate Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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