Prostate Carcinoma

Preferred Label : Prostate Carcinoma;

NCIt synonyms : Cancer of Prostate; Cancer of the Prostate; Carcinoma of the Prostate; Carcinoma of Prostate;

NCIt related terms : Prostate Cancer; Prostate cancer, NOS; Other Prostate Carcinoma;

NCIt definition : One of the most common malignant tumors afflicting men. The majority of carcinomas arise in the peripheral zone and a minority occur in the central or the transitional zone of the prostate gland. Grossly, prostatic carcinomas appear as ill-defined yellow areas of discoloration in the prostate gland lobes. Adenocarcinomas represent the overwhelming majority of prostatic carcinomas. Prostatic-specific antigen (PSA) serum test is widely used as a screening test for the early detection of prostatic carcinoma. Treatment options include radical prostatectomy, radiation therapy, androgen ablation and cryotherapy. Watchful waiting or surveillance alone is an option for older patients with low-grade or low-stage disease.;

Alternative definition : NCI-GLOSS: Cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men.;

Neoplastic status : Malignant;

Codes from synonyms : 10036910; CDR0000445079;

Details

Origin ID

C4863;

UMLS CUI

C0600139;

Automatic exact mappings (from CISMeF team)
- prostatic neoplasms [MeSH Descriptor]
Currated CISMeF NLP mapping
- Cancer of prostate [MedDRA LLT]
- Carcinoma of prostate (disorder) [SNOMED CT concept]
- Carcinoma prostate [MedDRA LLT]
- Carcinoma prostatic [MedDRA LLT]
- Malignant neoplasm of prostate [ICD-9 code]
- Malignant neoplasm of prostate [MedDRA LLT]
- Malignant neoplasm of prostate [ICD-10 category]
- Malignant tumor of prostate (disorder) [SNOMED CT concept]
- Primary malignant neoplasm of prostate (disorder) [SNOMED CT concept]
- Prostate cancer [PASCAL descriptor]
- Prostate cancer [HPO term]
- Prostate cancer [HPMULTI term]
- Prostate cancer [MedDRA Preferred Term]
- Prostate cancer [OMIM Phenotype]
- Prostate cancer NOS [MedDRA LLT]
- Prostate carcinoma [PASCAL descriptor]
- Prostate carcinoma [MedDRA LLT]
- Prostatic cancer [MedDRA LLT]
- Prostatic carcinoma [MedDRA LLT]
- Prostatic neoplasms malignant [MedDRA High Level Term]
- malignant neoplasm of prostate [SNOMED Notion]
- malignant neoplasm prostate [ICPC-2 Rubric]
- prostate cancer [Radlex concept]
- prostate cancer [DO Concept]
- prostate cancer [MedlinePlus Topic]
- prostate cancer [MeSH concept]
- prostate carcinoma [Disease (Nov.)]
- prostate carcinoma [DO Concept]
DO Cross reference
- prostate carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Carcinoma of prostate (disorder) [SNOMED CT concept]
- Carcinoma prostate [MedDRA LLT]
- Carcinoma prostatic [MedDRA LLT]
- Prostate carcinoma [MedDRA LLT]
- Prostate carcinoma [PASCAL descriptor]
- Prostatic carcinoma [MedDRA LLT]
- prostate carcinoma [DO Concept]
- prostate carcinoma [Disease (Nov.)]
Validated automatic mappings to NTBT
- Malignant neoplasms of prostate [ICD-11 Category]
- prostate cancer [Disease (Nov.)]
associated_with_malfunction_of_gene_product
- 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 [NCIt concept]
- Breast Cancer Type 1 Susceptibility Protein [NCIt concept]
- CD82 Antigen [NCIt concept]
- Catenin Beta-1 [NCIt concept]
- Caveolin-1 [NCIt concept]
- Cell Division Control Protein 6 Homolog [NCIt concept]
- Choline Kinase Alpha [NCIt concept]
- Collagen Alpha-1(XVIII) Chain [NCIt concept]
- Kallikrein-2 [NCIt concept]
- Rho GTPase-Activating Protein 7 [NCIt concept]
- Serine/Threonine-Protein Kinase Pim-1 [NCIt concept]
- T-Cell Receptor Gamma Chain Alternative Reading Frame Protein Isoform 1 [NCIt concept]
- Thymosin Beta-15A [NCIt concept]
- WAP Four-Disulfide Core Domain Protein 1 [NCIt concept]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Medical Conditions Codelist [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI CTEP SDC Prostate Cancer Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- Flutamide/Goserelin Regimen [NCIt concept]
- Flutamide/Leuprolide Regimen [NCIt concept]
disease_has_associated_gene
- CD82 Gene [NCIt concept]
- CD82 wt Allele [NCIt concept]
- CDC6 Gene [NCIt concept]
- CDC6 wt Allele [NCIt concept]
- CHKA Gene [NCIt concept]
- CHKA wt Allele [NCIt concept]
- MIR101-1 Gene [NCIt concept]
- MIR101-1 wt Allele [NCIt concept]
- MIR126 Gene [NCIt concept]
- MIR126 wt Allele [NCIt concept]
- MIR127 Gene [NCIt concept]
- MIR127 wt Allele [NCIt concept]
- MIR145 Gene [NCIt concept]
- MIR145 wt Allele [NCIt concept]
- MIR146A Gene [NCIt concept]
- MIR146A wt Allele [NCIt concept]
- MIR15A Gene [NCIt concept]
- MIR15A wt Allele [NCIt concept]
- MIR16-1 Gene [NCIt concept]
- MIR16-1 wt Allele [NCIt concept]
- MIR21 Gene [NCIt concept]
- MIR21 wt Allele [NCIt concept]
- MIR221 Gene [NCIt concept]
- MIR221 wt Allele [NCIt concept]
- MIR222 Gene [NCIt concept]
- MIR222 wt Allele [NCIt concept]
- MIR23B Gene [NCIt concept]
- MIR23B wt Allele [NCIt concept]
- MIR521-1 Gene [NCIt concept]
- MIR521-1 wt Allele [NCIt concept]
- MIR521-2 Gene [NCIt concept]
- MIR521-2 wt Allele [NCIt concept]
- MIRLET7C Gene [NCIt concept]
- MIRLET7C wt Allele [NCIt concept]
- MSMB Gene [NCIt concept]
- MSMB wt Allele [NCIt concept]
- PTEN Gene [NCIt concept]
- PTEN wt Allele [NCIt concept]
- S100P Gene [NCIt concept]
- S100P wt Allele [NCIt concept]
- SIPA1 Gene [NCIt concept]
- SIPA1 wt Allele [NCIt concept]
- SSTR4 Gene [NCIt concept]
- SSTR4 wt Allele [NCIt concept]
- TARP Gene [NCIt concept]
- TARP wt Allele [NCIt concept]
- TMPRSS2 Gene [NCIt concept]
- TMPRSS2 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Prostatic Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
has_biomarker_gene
- AGR2 wt Allele [NCIt concept]
- KLK11 wt Allele [NCIt concept]
- KLK15 Gene [NCIt concept]
- KLK15 wt Allele [NCIt concept]
- KLK2 wt Allele [NCIt concept]
- KLK3 Gene [NCIt concept]
- KLK3 wt Allele [NCIt concept]
- PCA3 Gene [NCIt concept]
- PCA3 wt Allele [NCIt concept]
has_biomarker_gene_product
- Prostate Cancer Antigen 3 [NCIt concept]
- Prostate-Specific Antigen [NCIt concept]
may_be_associated_disease_of_disease
- BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- CHEK2-Associated Li-Fraumeni-Like Syndrome [NCIt concept]
- Hereditary Tumor Syndrome Associated with Homologous Recombination Pathway Mutations [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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