Kallikrein-2 - CISMeF

Preferred Label : Kallikrein-2;

NCIt synonyms : KLK2; hGK-1; Kallikrein, Prostatic; Kallikrein 2, Prostatic; Glandular Kallikrein 2; Kallikrein 2; EC 3.4.21.35; hK2; Glandular Kallikrein-2 Precursor; Prostatic Kallikrein 2; Kallikrein, Glandular; Glandular Kallikrein-1; Tissue Kallikrein-2; Glandular Kallikrein 2 Precursor;

NCIt definition : Kallikrein-2 (261 aa, 29 kDa) is encoded by the human KLK2 gene. This protein plays a role in proteolysis and vasodilation.;

Details

Origin ID

C18163;

UMLS CUI

C0618743;

Currated CISMeF NLP mapping
- tissue kallikreins [MeSH Descriptor]
- tissue kallikreins [MeSH concept]
OMIM relation
- Kallikrein-related peptidase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- human glandular kallikrein 2 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- KLK2 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- Human Glandular Kallikrein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
gene_product_malfunction_associated_with_disease
- Prostate Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]
is_target
- Actinium Ac 225-DOTA-h11B6 JNJ-69086420 [NCIt concept]
- Anti-KLK2 CAR-T Cells JNJ-75229414 [NCIt concept]
- Anti-KLK2/CD3 Bispecific Antibody JNJ-78278343 [NCIt concept]
- Indium In 111-DOTA-h11B6 [NCIt concept]
- Kallikrein Inhibitor MDPK67b [NCIt concept]

Keyword's position in hierarchy(ies) :

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