Preferred Label : Kallikrein Inhibitor MDPK67b;
NCIt synonyms : KLK Inhibitor MDPK67b;
NCIt definition : A recombinant protein-based inhibitor of numerous types of kallikrein-related peptidases
(KLKs), with potential antineoplastic activity. Upon administration, KLK inhibitor
MDPK67b targets and inhibits various KLKs, including KLK2, KLK4, KLK5 and KLK14. This
inhibits KLK-mediated signaling and inhibits the proliferation of tumor cells in which
these KLKs are overexpressed. Deregulation of KLKs is associated with some types of
cancers.;
Molecule name : MDPK 67b; MDPK-67b;
NCI Metathesaurus CUI : CL1662948;
Origin ID : C180588;
UMLS CUI : C5556480;
Semantic type(s)
- concept_is_in_subset
- has_target
