Kallikrein - CISMeF

Preferred Label : Kallikrein;

NCIt synonyms : KLK; Kallikrein Enzyme Family; Kallikrein-Related Peptidase;

NCIt definition : Serine proteases that are found in many different tissues and fluids in the body. The kallikrein protease family is comprised of potent vasodilators and hypotensives agents, thus they play important roles in inflammation and blood pressure. These enzymes normally reside in the body as inactive prekallikreins, which are activated by Hageman factor.;

Details

Origin ID

C16767;

UMLS CUI

C5551415;

Automatic exact mappings (from CISMeF team)
- Kallikrein [ICHI extension code]
- kallikrein A [MeSH concept]
- kallikrein B' [MeSH concept]
- obsolete plasma kallikrein activity [GO term]
- obsolete tissue kallikrein activity [GO term]
- plasma kallikrein [MeSH Descriptor]
Biochemical function of gene products
- Kallikrein-10 [NCIt concept]
- Kallikrein-11 [NCIt concept]
- Kallikrein-15 [NCIt concept]
- Kallikrein-5 [NCIt concept]
- Kallikrein-6 [NCIt concept]
- Kallikrein-7 [NCIt concept]
- Plasma Kallikrein [NCIt concept]
- Prostate-Specific Antigen [NCIt concept]
Currated CISMeF NLP mapping
- Kallikrein [LOINC component]
- kallikrein [Substance BNPC]
- kallikrein [SNOMED Notion]
- kallikreins [MeSH Descriptor]
- kallikreins [MeSH concept]
False automatic mappings
- Kallikrein (substance) [SNOMED CT concept]
- kallikrein (11-23) [MeSH concept]
- kallikrein (11-23) [MeSH Supplementary Concept]
- kallikrein (328-343) [MeSH concept]
- kallikrein (328-343) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Kallikrein [ICD-11 Extension code]
- Kallikrein [LOINC component]
- Kallikrein (substance) [SNOMED CT concept]
- kallidinogenase [ATC Code]
- kallikrein [Substance BNPC]
- kallikrein [SNOMED Notion]
- kallikreins [MeSH concept]
- kallikreins [MeSH Descriptor]
Validated automatic mappings to BTNT
- Kallikrein [ICD-11 Extension code]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- Serine Protease [NCIt concept]
gene_product_plays_role_in_biological_process
- Proteolysis [NCIt concept]
is_target
- Kallikrein Inhibitor MDPK67b [NCIt concept]

Keyword's position in hierarchy(ies) :

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