Kallikrein-6 - CISMeF

Preferred Label : Kallikrein-6;

NCIt synonyms : KLK6; Serine Protease 9; Serine Protease 18; EC 3.4.21.-; Zyme; Neurosin; SP59; Protease M; Kallikrein 6;

NCIt definition : Kallikrein-6 (244 aa, 27 kDa) is encoded by the human KLK6 gene. This protein is involved in the proteolytic processing of substrates.;

NCIt note : Substrates for kallikrein-6 include alpha-synuclein, amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. (UniProt);

Details

Origin ID

C133891;

UMLS CUI

C0534101;

Automatic exact mappings (from CISMeF team)
- Kallikrein-related peptidase 6 [OMIM gene]
- M-protease [MeSH concept]
- buspirone [MeSH Descriptor]
- neurosine [MeSH concept]
OMIM relation
- Kallikrein-related peptidase 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KLK6 protein, human [MeSH Supplementary Concept]
- KLK6 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- KLK6 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kallikrein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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