Kallikrein-11 - CISMeF

Preferred Label : Kallikrein-11;

NCIt synonyms : EC 3.4.21.-; Trypsin-Like Protease; Trypsin-Like Serine Protease; Hippostasin; KLK11; hK11; Kallikrein 11; Serine Protease 20; Kallikrein-11 Precursor;

NCIt definition : Kallikrein-11 (282 aa, 31 kDa) is encoded by the human KLK11 gene. This protein plays a role in peptide metabolism.;

NCIt note : Efficiently cleaves bz-Phe-Arg-4-methylcoumaryl-7-amide, a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. (UniProt);

Details

Origin ID

C43297;

UMLS CUI

C1447694;

False automatic mappings
- HGF activator [MeSH Supplementary Concept]
OMIM relation
- Kallikrein-related peptidase 11 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KLK11 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- KLK11 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Prostate Gland [NCIt concept]
- Skin [NCIt concept]
gene_product_has_biochemical_function
- Kallikrein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Prognostic Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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