plasma kallikrein

Preferred Label : plasma kallikrein;

MeSH definition : A peptidohydrolytic enzyme that is formed from PREKALLIKREIN by FACTOR XIIA. It activates FACTOR XII; FACTOR VII; and PLASMINOGEN. It is selective for both ARGININE and to a lesser extent LYSINE bonds. EC 3.4.21.34.;

MeSH synonym : kallikrein, plasma; serum kallikrein; kallikrein, serum; kininogenin; kallikrein i;

Registry Number MeSH : EC 3.4.21.34;

Wikipedia link : https://en.wikipedia.org/wiki/Serum kallikrein;

Is substance : O;

UNII : EC 3.4.21.34;

Details

Origin ID

D020842;

UMLS CUI

C0313532;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Substance with kallikrein inhibitor mechanism of action (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Plasma Kallikrein [NCIt concept]
Indexing information
- PF 04886847 [MeSH Supplementary Concept]
Pharmacological action(s)
- coagulants [MeSH Descriptor]
Record concept(s)
- plasma kallikrein [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Plasma Kallikrein [NCIt concept]

Keyword's position in hierarchy(ies) :

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