Preferred Label : Anti-KLK2 CAR-T Cells JNJ-75229414;
NCIt synonyms : KLK2 CAR-T Cells JNJ-75229414; Anti-kallikrein-2 CAR T-cells JNJ-75229414; Anti-KLK2 CAR T Cells JNJ-75229414;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) targeting human kallikrein-2 (hK2; KLK2) expressed on tumor
cells, with potential immunostimulating and antineoplastic activities. Upon administration,
anti-KLK2 CAR-T cells JNJ-75229414 target and bind to KLK2-expressing tumor cells,
thereby inducing selective toxicity in KLK2-expressing tumor cells. KLK2 is overexpressed
in certain tumors, including prostate adenocarcinoma.;
Molecule name : JNJ-75229414; JNJ 75229414;
NCI Metathesaurus CUI : CL1771909;
Origin ID : C183544;
UMLS CUI : C5666915;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
