" /> AGR2 wt Allele - CISMeF





Preferred Label : AGR2 wt Allele;

NCIt synonyms : AGR2; HAG-2 Gene; XAG-2 Gene; AG2; XAG-2; PDIA17; HAG-2; GOB-4; HEL-S-116; Anterior Gradient 2 wt Allele; Protein Disulfide Isomerase Family A, Member 17 Gene; UNQ515/PRO1030; Anterior Gradient 2, Xenopus, Homolog of Gene; Anterior Gradient 2 Homolog Gene; Anterior Gradient 2 Homolog (Xenopus Laevis) Gene;

NCIt definition : Human AGR2 wild-type allele is located in the vicinity of 7p21.3 and is approximately 13 kb in length. This allele, which encodes anterior gradient protein 2 homolog protein, plays a role in the regulation of receptor adhesion and functioning. Overexpression of the AGR2 gene is associated with certain types of cancer such as breast and prostate cancer.;

NCIt note : Design Note: AGR2 gene expression is induced by both androgens and estrogen. This gene produces two mRNA transcripts via alternative splicing. However, both of the transcripts encode the same protein product. Overexpression of the AGR2 gene is associated with tumor metastasis.;

GenBank Accession Number : NM_006408;

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17/06/2025


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