Breast Carcinoma

Preferred Label : Breast Carcinoma;

NCIt synonyms : Cancer of Breast; Carcinoma of the Breast; Cancer of the Breast; Mammary Carcinoma; Carcinoma of Breast;

NCIt related terms : Breast Cancer; Breast cancer, NOS;

NCIt definition : A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla.;

Alternative definition : NICHD: A malignant neoplasm that develops or arises in breast tissue.; NCI-GLOSS: Cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare.;

Neoplastic status : Malignant;

FDA table : Patient Code (Appendix B);

Codes from synonyms : 10006285; CDR0000444971; 1759;

Details

Origin ID

C4872;

UMLS CUI

C0678222;

Automatic exact mappings (from CISMeF team)
- Breast Carcinoma [MeSH concept]
- Breast carcinoma [PASCAL descriptor]
- breast carcinoma [DO Concept]
- breast neoplasms [MeSH Descriptor]
- malignant neoplasm breast female [ICPC-2 Rubric]
- malignant neoplasm male genital other [ICPC-2 Rubric]
CISMeF manual mappings
- Carcinoma of breast (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Breast cancer [PASCAL descriptor]
- Breast cancer [HPMULTI term]
- Breast cancer [MedDRA Preferred Term]
- Breast cancer [OMIM Phenotype]
- Breast cancer NOS [MedDRA LLT]
- Breast carcinoma [HPO term]
- Breast carcinoma [MedDRA LLT]
- Breast carcinoma NOS [MedDRA LLT]
- Carcinoma breast [MedDRA LLT]
- Malignant neoplasm of breast [ICD-10 category (who)]
- Malignant neoplasm of breast [ICD-10 category]
- Malignant neoplasm of breast (disorder) [SNOMED CT concept]
- Malignant neoplasms of breast [Bloc CIM-11]
- breast cancer [Radlex concept]
- breast cancer [DO Concept]
- breast cancer [Disease (Nov.)]
- breast cancer [MedlinePlus Topic]
- breast cancer [MeSH concept]
DO Cross reference
- breast carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Breast carcinoma [MedDRA LLT]
- Breast carcinoma [HPO term]
- Breast carcinoma NOS [MedDRA LLT]
- Carcinoma breast [MedDRA LLT]
- Carcinoma of breast (disorder) [SNOMED CT concept]
- breast carcinoma [DO Concept]
associated_with_malfunction_of_gene_product
- Anterior Gradient Protein 2 Homolog [NCIt concept]
- Antigen Peptide Transporter 1 [NCIt concept]
- BRCA1-Associated RING Domain Protein 1 [NCIt concept]
- Breast Cancer Anti-Estrogen Resistance Protein 1 [NCIt concept]
- Breast Cancer Type 1 Susceptibility Protein [NCIt concept]
- Breast Carcinoma-Amplified Sequence 1 [NCIt concept]
- Breast Carcinoma-Amplified Sequence 3 [NCIt concept]
- Breast Carcinoma-Amplified Sequence 4 [NCIt concept]
- Cadherin-1 [NCIt concept]
- Catechol O-Methyltransferase [NCIt concept]
- Cathepsin D [NCIt concept]
- Cellular Tumor Antigen p53 [NCIt concept]
- Choline Kinase Alpha [NCIt concept]
- DNA Repair and Recombination Protein RAD54-Like [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 11 [NCIt concept]
- E3 Ubiquitin/ISG15 Ligase TRIM25 [NCIt concept]
- Epithelial Discoidin Domain-Containing Receptor 1 [NCIt concept]
- G Antigen Family D Member 3 [NCIt concept]
- GRB2-Associated-Binding Protein 2 [NCIt concept]
- Gamma-Synuclein [NCIt concept]
- Hyaluronan Mediated Motility Receptor [NCIt concept]
- Lactadherin [NCIt concept]
- Metastasis-Suppressor KiSS-1 [NCIt concept]
- Methylated-DNA-Protein-Cysteine Methyltransferase [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Protein CASC3 [NCIt concept]
- Protein S100-A2 [NCIt concept]
- Protein TSSC4 [NCIt concept]
- RB1-Inducible Coiled-Coil Protein 1 [NCIt concept]
- RNA-Binding Protein Nova-1 [NCIt concept]
- Rho GTPase-Activating Protein 7 [NCIt concept]
- Serine-Protein Kinase ATM [NCIt concept]
- T-Cell Receptor Gamma Chain Alternative Reading Frame Protein Isoform 1 [NCIt concept]
- TNF Receptor-Associated Factor 4 [NCIt concept]
- Tetraspanin-32 [NCIt concept]
- Transforming Acidic Coiled-Coil-Containing Protein 1 [NCIt concept]
- Trefoil Factor 1 [NCIt concept]
- Tumor Susceptibility Gene 101 Protein [NCIt concept]
- WAP Four-Disulfide Core Domain Protein 1 [NCIt concept]
concept_is_in_subset
- CDRH Health Effects - Clinical Signs and Syptoms or Conditions Terminology [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Medical Conditions Codelist [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- FDA Center For Devices and Radiological Health Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI CTEP SDC Breast Neoplasm, Miscellaneous Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- AC Regimen [NCIt concept]
- CMF Regimen [NCIt concept]
- Capecitabine/Docetaxel Regimen [NCIt concept]
- Cyclophosphamide/Epirubicin Regimen [NCIt concept]
- Docetaxel/Doxorubicin Regimen [NCIt concept]
- Docetaxel/Vandetanib Regimen [NCIt concept]
- E-CMF Regimen [NCIt concept]
disease_has_associated_disease
- Angiosarcoma of the Skin of the Arm after Radical Mastectomy followed by Lymphedema [NCIt concept]
disease_has_associated_gene
- ADAM11 Gene [NCIt concept]
- ADAM11 wt Allele [NCIt concept]
- AGR2 Gene [NCIt concept]
- AGR2 wt Allele [NCIt concept]
- ANKRD30A Gene [NCIt concept]
- ANKRD30A wt Allele [NCIt concept]
- APPBP2 Gene [NCIt concept]
- APPBP2 wt Allele [NCIt concept]
- ATM Gene [NCIt concept]
- ATM wt Allele [NCIt concept]
- AXIN2 Gene [NCIt concept]
- AXIN2 wt Allele [NCIt concept]
- BCAR1 Gene [NCIt concept]
- BCAR1 wt Allele [NCIt concept]
- BCAR3 Gene [NCIt concept]
- BCAR3 wt Allele [NCIt concept]
- BCAS1 Gene [NCIt concept]
- BCAS1 wt Allele [NCIt concept]
- BCAS2 Gene [NCIt concept]
- BCAS2 wt Allele [NCIt concept]
- BCAS3 Gene [NCIt concept]
- BCAS3 wt Allele [NCIt concept]
- BCAS4 Gene [NCIt concept]
- BCAS4 wt Allele [NCIt concept]
- BRCA3 Gene [NCIt concept]
- BRCATA Gene [NCIt concept]
- BRCD1 Gene [NCIt concept]
- BRMS1 Gene [NCIt concept]
- BRMS1 wt Allele [NCIt concept]
- CALML4 Gene [NCIt concept]
- CALML4 wt Allele [NCIt concept]
- CASC3 Gene [NCIt concept]
- CASC3 wt Allele [NCIt concept]
- CDH13 Gene [NCIt concept]
- CDH13 wt Allele [NCIt concept]
- CDH5 Gene [NCIt concept]
- CDH5 wt Allele [NCIt concept]
- CHKA Gene [NCIt concept]
- CHKA wt Allele [NCIt concept]
- CHMP2A Gene [NCIt concept]
- CHMP2A wt Allele [NCIt concept]
- CLCA2 Gene [NCIt concept]
- CLCA2 wt Allele [NCIt concept]
- CST6 Gene [NCIt concept]
- CST6 wt Allele [NCIt concept]
- CTSD Gene [NCIt concept]
- CTSD wt Allele [NCIt concept]
- FGFR4 Gene [NCIt concept]
- FGFR4 wt Allele [NCIt concept]
- HYOU1 Gene [NCIt concept]
- HYOU1 wt Allele [NCIt concept]
- KISS1 Gene [NCIt concept]
- KISS1 wt Allele [NCIt concept]
- MIR10B Gene [NCIt concept]
- MIR10B wt Allele [NCIt concept]
- MIR124-1 Gene [NCIt concept]
- MIR124-1 wt Allele [NCIt concept]
- MIR125A Gene [NCIt concept]
- MIR125A wt Allele [NCIt concept]
- MIR126 Gene [NCIt concept]
- MIR126 wt Allele [NCIt concept]
- MIR127 Gene [NCIt concept]
- MIR127 wt Allele [NCIt concept]
- MIR141 Gene [NCIt concept]
- MIR141 wt Allele [NCIt concept]
- MIR146A Gene [NCIt concept]
- MIR146A wt Allele [NCIt concept]
- MIR146B Gene [NCIt concept]
- MIR146B wt Allele [NCIt concept]
- MIR155 Gene [NCIt concept]
- MIR155 wt Allele [NCIt concept]
- MIR17 Gene [NCIt concept]
- MIR17 wt Allele [NCIt concept]
- MIR200A Gene [NCIt concept]
- MIR200A wt Allele [NCIt concept]
- MIR200B Gene [NCIt concept]
- MIR200B wt Allele [NCIt concept]
- MIR200C Gene [NCIt concept]
- MIR200C wt Allele [NCIt concept]
- MIR204 Gene [NCIt concept]
- MIR204 wt Allele [NCIt concept]
- MIR205 Gene [NCIt concept]
- MIR205 wt Allele [NCIt concept]
- MIR206 Gene [NCIt concept]
- MIR206 wt Allele [NCIt concept]
- MIR20A Gene [NCIt concept]
- MIR20A wt Allele [NCIt concept]
- MIR21 Gene [NCIt concept]
- MIR21 wt Allele [NCIt concept]
- MIR210 Gene [NCIt concept]
- MIR210 wt Allele [NCIt concept]
- MIR214 Gene [NCIt concept]
- MIR214 wt Allele [NCIt concept]
- MIR221 wt Allele [NCIt concept]
- MIR222 Gene [NCIt concept]
- MIR222 wt Allele [NCIt concept]
- MIR27A Gene [NCIt concept]
- MIR27A wt Allele [NCIt concept]
- MIR27B Gene [NCIt concept]
- MIR27B wt Allele [NCIt concept]
- MIR335 Gene [NCIt concept]
- MIR335 wt Allele [NCIt concept]
- MIR429 Gene [NCIt concept]
- MIR429 wt Allele [NCIt concept]
- MIR451A Gene [NCIt concept]
- MIR451A wt Allele [NCIt concept]
- MIR510 Gene [NCIt concept]
- MIR510 wt Allele [NCIt concept]
- MIR516A1 Gene [NCIt concept]
- MIR516A1 wt Allele [NCIt concept]
- MIR516A2 Gene [NCIt concept]
- MIR516A2 wt Allele [NCIt concept]
- MIR516B1 Gene [NCIt concept]
- MIR516B1 wt Allele [NCIt concept]
- MIR520C Gene [NCIt concept]
- MIR520C wt Allele [NCIt concept]
- MIR7-1 Gene [NCIt concept]
- MIR7-1 wt Allele [NCIt concept]
- MIR7-2 Gene [NCIt concept]
- MIR7-2 wt Allele [NCIt concept]
- MIR7-3 Gene [NCIt concept]
- MIR7-3 wt Allele [NCIt concept]
- MIRLET7A1 Gene [NCIt concept]
- MIRLET7A1 wt Allele [NCIt concept]
- MIRLET7A3 Gene [NCIt concept]
- MIRLET7A3 wt Allele [NCIt concept]
- NOVA1 Gene [NCIt concept]
- NOVA1 wt Allele [NCIt concept]
- PDZK1IP1 Gene [NCIt concept]
- PDZK1IP1 wt Allele [NCIt concept]
- PPM1D Gene [NCIt concept]
- PPM1D wt Allele [NCIt concept]
- PTK6 Gene [NCIt concept]
- PTK6 wt Allele [NCIt concept]
- RAD54L Gene [NCIt concept]
- RAD54L wt Allele [NCIt concept]
- RB1CC1 Gene [NCIt concept]
- RB1CC1 wt Allele [NCIt concept]
- S100A2 Gene [NCIt concept]
- S100A2 wt Allele [NCIt concept]
- SNCG Gene [NCIt concept]
- SNCG wt Allele [NCIt concept]
- STK11 Gene [NCIt concept]
- STK11 wt Allele [NCIt concept]
- TAP1 Gene [NCIt concept]
- TAP1 wt Allele [NCIt concept]
- TARP Gene [NCIt concept]
- TARP wt Allele [NCIt concept]
- TFF1 Gene [NCIt concept]
- TFF1 wt Allele [NCIt concept]
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]
- TPD52 Gene [NCIt concept]
- TPD52 wt Allele [NCIt concept]
- TPD52L1 Gene [NCIt concept]
- TPD52L1 wt Allele [NCIt concept]
- TRERF1 Gene [NCIt concept]
- TRERF1 wt Allele [NCIt concept]
- TSG101 Gene [NCIt concept]
- TSG101 wt Allele [NCIt concept]
- TSPAN32 Gene [NCIt concept]
- TSPAN32 wt Allele [NCIt concept]
- TSSC4 Gene [NCIt concept]
- TSSC4 wt Allele [NCIt concept]
- WNT10B Gene [NCIt concept]
- WNT10B wt Allele [NCIt concept]
- WNT3 Gene [NCIt concept]
- WNT3 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
has_biomarker_gene
- KLK15 wt Allele [NCIt concept]
has_biomarker_gene_product
- Haptoglobin-Related Protein [NCIt concept]
may_be_associated_disease_of_disease
- BRCA1-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- Bannayan-Riley-Ruvalcaba Syndrome [NCIt concept]
- CHEK2-Associated Li-Fraumeni-Like Syndrome [NCIt concept]
- Cowden Syndrome [NCIt concept]
- Hereditary Gastric Diffuse Adenocarcinoma [NCIt concept]
- Hereditary Tumor Syndrome Associated with Homologous Recombination Pathway Mutations [NCIt concept]
- Li-Fraumeni Syndrome [NCIt concept]
- Multiple Endocrine Neoplasia Type 5 [NCIt concept]
- Neurofibromatosis Type 1 [NCIt concept]
- Neurofibromatosis Type 1 with Inoperable, Progressive, Symptomatic Plexiform Neurofibromas [NCIt concept]
- PTEN Hamartoma Tumor Syndrome [NCIt concept]
- Peutz-Jeghers Syndrome [NCIt concept]
- Proteus-Like Syndrome [NCIt concept]
- Recurrent Neurofibromatosis Type 1 [NCIt concept]
- Refractory Neurofibromatosis Type 1 [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]

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