Breast Cancer Anti-Estrogen Resistance Protein 1

Preferred Label : Breast Cancer Anti-Estrogen Resistance Protein 1;

NCIt synonyms : CAS; BCAR1 Protein; BCAR1; p130CAS; CRK-Associated Substrate; CRKAS; Crk-Associated Substrate p130Cas; Breast Cancer Anti-Estrogen Resistance-1 Protein; Breast Cancer Anti-Estrogen Resistance 1 Protein; Cas Scaffolding Protein Family Member 1;

NCIt definition : Breast cancer anti-estrogen resistance protein 1 (870 aa, 93 kDa) is encoded by the human BCAR1 gene. This protein plays a role in the propagation of cell adhesion-dependent tyrosine-protein kinase signaling.;

Details

Origin ID

C21491;

UMLS CUI

C1451357;

Automatic exact mappings (from CISMeF team)
- 6-chloropenicillanic acid S-sulfoxide [MeSH Supplementary Concept]
- 6-chloropenicillanic acid S-sulfoxide [MeSH concept]
- BCAR1 scaffold protein, Cas family member [HGNC gene]
- Bcar1 scaffold protein, cas family member [OMIM gene]
- CAS [LOINC method]
- CAS number [EDAM data]
- Calcium [MedDRA LLT]
- Catenin, delta-1 [OMIM gene]
- Chromosome segregation 1-like [OMIM gene]
- Cold agglutinin disease [ORDO Disease]
- Crk-Associated substrate protein [MeSH concept]
- Isolated childhood apraxia of speech [ORDO Disease]
- Palmoplantar keratoderma and congenital alopecia 2 [OMIM Phenotype]
- Speech-language disorder 1 [OMIM Phenotype]
- callosal sulcus [UBERON concept]
- crk-associated substrate protein [MeSH Descriptor]
- glutaryl-7-aminocephalosporanic-acid acylase activity [GO term]
- obsolete importin, alpha-subunit transport factor [GO term]
- speech-language disorder-1 [DO Concept]
False automatic mappings
- Ca++ [MedDRA LLT]
OMIM relation
- Bcar1 scaffold protein, cas family member [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BCAR1 protein, human [MeSH concept]
- BCAR1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- BCAR1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Helix-Loop-Helix Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
- SH2-Binding Motif [NCIt concept]
- SH3 Domain [NCIt concept]
- YDYVHL Motif [NCIt concept]
- YXXP Motif [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- CXCR4 Signaling Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell to Cell Adhesion Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Endothelin Pathway [NCIt concept]
- Ephrin A2 Forward Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IGF1 Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- PTEN-Dependent Cell Cycle Arrest and Apoptosis Pathway [NCIt concept]
- PTP4A Family Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Plasma Membrane Estrogen Receptor Signaling Pathway [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Motility [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Embryogenesis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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