GRB2-Associated-Binding Protein 2

Preferred Label : GRB2-Associated-Binding Protein 2;

NCIt synonyms : GAB2 Protein; GAB2; GRB2-Associated Binding Protein-2; Growth Factor Receptor Bound Protein 2-Associated Protein 2; GRB2-Associated Binding Protein 2; pp100; GRB2-Associated Binder 2;

NCIt definition : GRB2-associated-binding protein 2 (676 aa, 74 kDa) is encoded by the human GAB2 gene. This protein plays a role in the modulation of multiple signaling pathways.;

Details

Origin ID

C26192;

UMLS CUI

C0387800;

Automatic exact mappings (from CISMeF team)
- GRB2 associated binding protein 2 [HGNC gene]
- Grb2-associated binding protein 2 [OMIM gene]
OMIM relation
- Grb2-associated binding protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GAB2 protein, human [MeSH concept]
- GAB2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- GAB2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- SH3-Binding Motif [NCIt concept]
gene_product_is_element_in_pathway
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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