Cathepsin D - CISMeF

Preferred Label : Cathepsin D;

NCIt synonyms : CTSD; Epididymis Secretory Sperm Binding Protein Li 130P; EC 3.4.23.5; Cathepsin-D;

NCIt definition : Cathepsin D (412 aa, 45 kDa) is encoded by the human CTSD gene. This protein is involved in proteolysis.;

NCIt note : Cathepsin D is a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor.;

Details

Origin ID

C16388;

UMLS CUI

C2606220;

Currated CISMeF NLP mapping
- Cathepsin D [LOINC component]
- cathepsin D [MeSH concept]
- cathepsin d [MeSH Descriptor]
- cathepsin d [SNOMED Notion]
False automatic mappings
- Cathepsin D (substance) [SNOMED CT concept]
OMIM relation
- Cathepsin D [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CTSD protein, human [MeSH Supplementary Concept]
- CTSD protein, human [MeSH concept]
- Cathepsin D [LOINC component]
- Cathepsin D (substance) [SNOMED CT concept]
- cathepsin D [MeSH concept]
- cathepsin d [SNOMED Notion]
- cathepsin d [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CTSD Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ceramide Signaling Pathway PID [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
- MTA3 Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Ovarian Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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