Ovarian Carcinoma

Preferred Label : Ovarian Carcinoma;

NCIt synonyms : Carcinoma of Ovary; Carcinoma of the Ovary;

NCIt related terms : Ovarian Cancer; epithelial ovarian cancer; Ovarian epithelial cancer;

NCIt definition : A malignant neoplasm originating from the surface ovarian epithelium. It accounts for the greatest number of deaths from malignancies of the female genital tract and is the fifth leading cause of cancer fatalities in women. It is predominantly a disease of older white women of northern European extraction, but it is seen in all ages and ethnic groups. Adenocarcinomas constitute the vast majority of ovarian carcinomas. The pattern of metastatic spread in ovarian carcinoma is similar regardless of the microscopic type. The most common sites of involvement are the contralateral ovary, peritoneal cavity, para-aortic and pelvic lymph nodes, and liver. Lung and pleura are the most common sites of extra-abdominal spread. The primary form of therapy is surgical. The overall prognosis of ovarian carcinoma remains poor, a direct result of its rapid growth rate and the lack of early symptoms.;

Alternative definition : NCI-GLOSS: Cancer that occurs in the cells lining the ovaries.;

Neoplastic status : Malignant;

Codes from synonyms : 10033159; CDR0000046768; CDR0000045683;

Details

Origin ID

C4908;

UMLS CUI

C4721610;

Automatic exact mappings (from CISMeF team)
- Carcinoma, Ovarian Epithelial [MeSH concept]
- Carcinoma, Ovarian Epithelial [MeSH Descriptor]
- Malignant epithelial tumor of ovary [ORDO Disease]
- Malignant epithelial tumor of ovary (disorder) [SNOMED CT concept]
- Ovarian epithelial cancer [MedDRA Preferred Term]
Currated CISMeF NLP mapping
- Cancer of ovary [MedDRA LLT]
- Carcinomas of ovary [ICD-11 Subcategory]
- Malignant neoplasm of ovary [MedDRA LLT]
- Malignant neoplasm of ovary [ICD-10 category]
- Malignant neoplasm of ovary [ICD-9 code]
- Malignant tumor of ovary (disorder) [SNOMED CT concept]
- OVARIAN CARCINOMA [WHO-ART Preferred Term]
- Ovarian cancer [MedDRA Preferred Term]
- Ovarian cancer [ORDO Disease]
- Ovarian cancer [OMIM Phenotype]
- Ovarian cancer NOS [MedDRA LLT]
- Ovarian carcinoma [HPO term]
- Ovarian carcinoma [MedDRA LLT]
- Ovarian neoplasm [HPO term]
- Ovary cancer [PASCAL descriptor]
- Ovary carcinoma [PASCAL descriptor]
- Primary malignant neoplasm of ovary (disorder) [SNOMED CT concept]
- malignant neoplasm of ovary [SNOMED Notion]
- ovarian cancer [MedlinePlus Topic]
- ovarian cancer [Radlex concept]
- ovarian cancer [DO Concept]
- ovarian carcinoma [TUV Concept]
- ovarian carcinoma [TUV Term]
- ovarian carcinoma [DO Concept]
- ovarian neoplasms [MeSH Descriptor]
- ovary cancer [MeSH concept]
- ovary carcinoma [Disease (Nov.)]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Abdominal Mass [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
HPO term
- Ovarian carcinoma [HPO term]
Has associated anatomic sites
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Ovary [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Carcinoma, Ovarian Epithelial [MeSH concept]
- Carcinoma, Ovarian Epithelial [MeSH Descriptor]
- Malignant epithelial tumor of ovary [ORDO Disease]
- Ovarian carcinoma [HPO term]
- Ovarian epithelial cancer [MedDRA Preferred Term]
- Ovarian epithelial cancer NOS [MedDRA LLT]
- ovarian carcinoma [DO Concept]
Validated automatic mappings to NTBT
- Malignant neoplasms of ovary [ICD-11 Category]
associated_with_malfunction_of_gene_product
- BRCA1-Associated RING Domain Protein 1 [NCIt concept]
- Cathepsin D [NCIt concept]
- Deoxycytidine Kinase [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 11 [NCIt concept]
- Protein TSSC4 [NCIt concept]
- RAC-Beta Serine/Threonine Kinase [NCIt concept]
- Tetraspanin-32 [NCIt concept]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- NCI CTEP SDC Ovarian Cancer (excluding Ovarian Germ Cell Cancer) Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- BEP Regimen [NCIt concept]
- Carboplatin/Docetaxel Regimen [NCIt concept]
- Carboplatin/Gemcitabine Regimen [NCIt concept]
- Carboplatin/Liposomal Doxorubicin Regimen [NCIt concept]
- Carboplatin/Paclitaxel Regimen [NCIt concept]
- Cisplatin/Gemcitabine Regimen [NCIt concept]
- Cisplatin/Paclitaxel Regimen [NCIt concept]
- Liposomal Doxorubicin/Gemcitabine Regimen [NCIt concept]
- PEB Regimen [NCIt concept]
disease_has_associated_gene
- AKT2 Gene [NCIt concept]
- AKT2 wt Allele [NCIt concept]
- CDH1 Gene [NCIt concept]
- CDH1 wt Allele [NCIt concept]
- CTSD Gene [NCIt concept]
- CTSD wt Allele [NCIt concept]
- ERBB2 Gene [NCIt concept]
- ERBB2 wt Allele [NCIt concept]
- MIR146A Gene [NCIt concept]
- MIR146A wt Allele [NCIt concept]
- MIR199A1 Gene [NCIt concept]
- MIR199A1 wt Allele [NCIt concept]
- MIR199A2 Gene [NCIt concept]
- MIR199A2 wt Allele [NCIt concept]
- MIR221 Gene [NCIt concept]
- MIR221 wt Allele [NCIt concept]
- MIR223 Gene [NCIt concept]
- MIR223 wt Allele [NCIt concept]
- MIR337 Gene [NCIt concept]
- MIR337 wt Allele [NCIt concept]
- MIR34B Gene [NCIt concept]
- MIR34B wt Allele [NCIt concept]
- MIR34C Gene [NCIt concept]
- MIR34C wt Allele [NCIt concept]
- MIR376A1 Gene [NCIt concept]
- MIR376A1 wt Allele [NCIt concept]
- MIR376B Gene [NCIt concept]
- MIR376B wt Allele [NCIt concept]
- MIR377 Gene [NCIt concept]
- MIR377 wt Allele [NCIt concept]
- MIR432 Gene [NCIt concept]
- MIR432 wt Allele [NCIt concept]
- MIRLET7A1 Gene [NCIt concept]
- MIRLET7A1 wt Allele [NCIt concept]
- MIRLET7A3 Gene [NCIt concept]
- MIRLET7A3 wt Allele [NCIt concept]
- MIRLET7C Gene [NCIt concept]
- MIRLET7C wt Allele [NCIt concept]
- MIRLET7D Gene [NCIt concept]
- MIRLET7D wt Allele [NCIt concept]
- MIRLET7G Gene [NCIt concept]
- MIRLET7G wt Allele [NCIt concept]
- MIRLET7I Gene [NCIt concept]
- MIRLET7I wt Allele [NCIt concept]
- RRAS2 wt Allele [NCIt concept]
- TSPAN32 Gene [NCIt concept]
- TSPAN32 wt Allele [NCIt concept]
- TSSC4 Gene [NCIt concept]
- TSSC4 wt Allele [NCIt concept]
- WNT6 Gene [NCIt concept]
- WNT6 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Stromal Invasion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Ovarian Surface Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Ovary [NCIt concept]
disease_may_have_associated_disease
- Endometrial Carcinoma [NCIt concept]
has_biomarker_gene
- KLK11 wt Allele [NCIt concept]
- KLK15 wt Allele [NCIt concept]
may_be_associated_disease_of_disease
- BRCA1-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome [NCIt concept]
- Hereditary Tumor Syndrome Associated with Homologous Recombination Pathway Mutations [NCIt concept]
- Lynch 1 Syndrome [NCIt concept]
- Lynch 2 Syndrome [NCIt concept]
- Lynch Syndrome [NCIt concept]
- Peutz-Jeghers Syndrome [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]

Keyword's position in hierarchy(ies) :

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