NCIt synonyms : RAS Related 2 wt Allele; TC21; Teratocarcinoma Oncogene TC21 Gene; Related RAS Viral Oncogene Homolog 2 Gene; NS12; Related RAS Viral (r-ras) Oncogene Homolog 2 Gene;
NCIt definition : Human RRAS2 wild-type allele is located in the vicinity of 11p15.2 and is approximately
80 kb in length. This allele, which encodes Ras-related protein R-Ras2, may play a
role in both phosphatidylinositol-mediated signal transduction and nuclear factor
kappa B complex pathway attenuation. A point mutation in the gene is associated with
ovarian cancer.;