Disintegrin and Metalloproteinase Domain-Containing Protein 11

Preferred Label : Disintegrin and Metalloproteinase Domain-Containing Protein 11;

NCIt synonyms : A Disintegrin and Metalloproteinase Domain 11 Protein; Metalloproteinase-Like, Disintegrin-Like and Cysteine-Rich Protein; ADAM11; ADAM11 Protein; MDC; ADAM 11;

NCIt definition : Disintegrin and metalloproteinase domain-containing protein 11 (769 aa, 83 kDa) is encoded by the human ADAM11 gene. This protein plays a role in integrin-mediated signaling.;

NCIt note : Disintegrin and metalloproteinase domain-containing protein 11 has a non-catalytic metalloprotease domain. (UniProt);

Details

Origin ID

C25799;

UMLS CUI

C0290378;

OMIM relation
- A disintegrin and metalloproteinase domain 11 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ADAM11 protein, human [MeSH concept]
- ADAM11 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ADAM11 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- ADAM Family Protein [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ADAM Type Metalloprotease Domain [NCIt concept]
- Disintegrin Domain [NCIt concept]
- EGF-Like Domain [NCIt concept]
- Metal Binding Site [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Ovarian Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Fertilization [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Myogenesis [NCIt concept]
- Neural Development [NCIt concept]

Keyword's position in hierarchy(ies) :

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